Praise him with the timbrel - Hebrew, תף tôph. See this described in the notes at Isaiah 5:12. It is rendered tabret and tabrets in Genesis 31:27; 1-Samuel 10:5; 1-Samuel 18:6; Isaiah 5:12; Isaiah 24:8; Isaiah 30:32; Jeremiah 31:4; Ezekiel 28:13; timbrel and timbrels in Exodus 15:20; Judges 11:34; 2-Samuel 6:5; 1-Chronicles 13:8; Job 21:12; Psalm 81:2; Psalm 149:3; and in the margin in Jeremiah 31:4. The word does not occur elsewhere. It was an instrument that was struck with the hands.
And dance - See this word explained in the notes at Psalm 149:3. Dancing among the Hebrews seems to have accompanied the timbrel or tabret. See Exodus 15:20,
Praise him with stringed instruments - מנים minniym. This word means strings, from a verb which means to divide; and the proper reference would be to slender threads, as if they were divided, or made small. It is nowhere else applied to instruments of music, but might be properly applied to a harp, a violin, a bass-viol, etc. The word strings is indeed applied elsewhere to instruments of music Psalm 33:2; Psalm 144:9; 1-Samuel 18:16; Isaiah 38:20; Habakkuk 3:19, but the Hebrew word is different. Such instruments were commonly used in the praise of God. See the notes at Psalm 33:2.
And organs - Hebrew, עוגב ‛ûgâb. See this word explained in the notes at Job 21:12. It occurs elsewhere only in Genesis 4:21; Job 21:12; Job 30:31; in all of which places it is rendered organ. The word is derived from a verb meaning to breathe, to blow; and would be applicable to any wind-instrument. It here represents the whole class of wind-instruments. The word organ is a Greek word, and is found in the Septuagint in this place; and hence, our word organ has been introduced into the translation. The Greek word properly denotes
(a) something by which work is accomplished, as a machine;
(b) a musical instrument;
(c) the material from which anything is made;
(d) the work itself. (Passow, Lexicon).
Our word organ, as used in music, suggests the idea of a combination of instruments or sounds. That idea is not found in the Hebrew word. It denotes merely a wind-instrument. Neither the Hebrews nor any of the ancient nations had an instrument that corresponded with the organ as we now use the term.

Praise him with the timbrel - תף toph, drum, tabret, or tomtom, or tympanum of the ancients; a skin stretched over a broad hoop; perhaps something like the tambarine. Anglo-Saxon; the glad pipe. Taburne; Old Psalter.
And dance - מחול machol, the pipe. The croude or crowthe: Old Psalter; a species of violin. It never means dance; see the note on Psalm 149:3. Crwth signifies a fiddle in Welsh.
Stringed instruments - מנים minnim. This literally signifies strings put in order; perhaps a triangular kind of hollow instrument on which the strings were regularly placed, growing shorter and shorter till they came to a point. This would give a variety of sounds, from a deep bass to a high treble. In an ancient MS. Psalter before me, David is represented in two places, playing on such an instrument. It may be the sambuck, or psaltery, or some such instrument.
Organs - עוגב ugab. Very likely the syrinx or mouth organ; Pan's pope; both of the ancients and moderns. The fistula, septem, disparibus nodis conjuncta, made of seven pieces of cane or thick straw, of unequal lengths, applied to the lips, each blown into, according to the note intended to be expressed. This instrument is often met with in the ancient bucolic or pastoral writers.

Praise him with the timbrel and dance,.... Or "pipe" (u); See Gill on Psalm 149:3;
praise him with stringed instruments; or divers "kinds" (w) of instruments not named, as R. Saadiah Gaon; and which, as Aben Ezra says, had all one sound or note; what they were is not known, as also many of them that are particularly mentioned;
and organs; which have their name from the loveliness of their sound; these are of ancient original and use, Genesis 4:21; but were not of the same kind with those now in use, which are of much later invention.
(u) "et tibia", Tigurine version, Junius & Tremellius, Piscator, Gejerus. (w) "varia symphonia", Cocceius.

organs--or pipe, a wind instrument, and the others were used in worship.