My harp also is turned to mourning - What formerly gave cheerful sounds, now gives only notes of plaintiveness and lamentation. The harp was probably an instrument originally designed to give sounds of joy. For a description of it, see the notes at Isaiah 5:12.
And my organ - The form of what is here called the organ, is not certainly known. The word עגב ‛ûgâb is doubtless from עגב ‛âgab, "to breathe, to blow"; and most probably the instrument hero intended was the pipe. For a description of it, see the notes at Isaiah 5:12. This instrument, also, was played, as would appear, on joyous occasions, but Job now says that it was turned to grief. All that had been joyous with him had fled. His honor was taken away; his friends were gone; they who had treated him with reverence now stood at a distance, or treated him with contempt; his health was departed, and his former appearance, indicating a station of affluence, was changed for the dark complexion produced by disease, and the instruments of joyousness now gave forth only notes of sorrow.

My harp also is turned to mourning - Instead of the harp, my only music is my own plaintive cries.
And my organ - What the עגב uggab was, we know not; it was most probably some sort of pipe or wind instrument. His harp, כנור kinnor, and his pipe, עגב uggab, were equally mute, or only used for mournful ditties.
This chapter is full of the most painful and pathetic sorrow; but nevertheless tempered with a calmness and humiliation of spirit, which did not appear in Job's lamentations previously to the time in which he had that remarkable revelation mentioned in the nineteenth chapter. (Job 19:25) After he was assured that his Redeemer was the living God, he submitted to his dispensations, kissed the rod, and mourned not without hope, though in deep distress, occasioned by his unremitting sufferings. If the groaning of Job was great, his stroke was certainly heavy.

My harp also is turned to mourning,.... Which he used, as David, either in religious worship, expressing praise to God thereby, or for his recreation in an innocent way; but now it was laid aside, and, instead of it, nothing was heard from him, or in his house, but the voice of mourning:
and my organ into the voice of them that weep; another instrument of music, which had its name from the pleasantness of its sound, and was of early use, being first invented by Jubal, Genesis 4:21; but not that we now so call, which is of late invention: those instruments which Job might have and use, both in a civil and in a religious way, were now, through afflictions, become useless to him, and neglected by him; or these expressions in general may signify, that, instead of mirth and joy he was wont to have, there were nothing now to be heard but lamentation and woe; see Lamentations 5:15.

organ--rather, "pipe" (Job 21:12). "My joy is turned into the voice of weeping" (Lamentations 5:15). These instruments are properly appropriated to joy (Isaiah 30:29, Isaiah 30:32), which makes their use now in sorrow the sadder by contrast.