Let my prayer come into thy presence. After having made supplication that the gift of right understanding might be imparted to him, the Psalmist now implores God for deliverance, by which he acknowledges that he was continually involved in multiplied dangers from which he found it impossible to escape, unless God stretched forth his hand from heaven to his aid. We know, indeed, that whenever any distress was pressing hard behind him, he called upon God for succor; but as he does not here specify any particular distress, I have no doubt that, in commending his life in general terms to the protection of God, he thought again and again how he was shut up on every side by innumerable deaths, from which he could not escape if God did not prove his continual deliverer. But this is an inestimable comfort to us, that God assures us that in all dangers he will be ready and prepared to help us.

Let my supplication come before thee - The word here rendered "supplication" properly means "favor, mercy, pity," Joshua 11:20; Ezra 9:8; then, that by which favor or mercy is sought - prayer or petition, Psalm 6:9; Psalm 55:1.
Deliver me according to thy word - From my enemies, my sins, my dangers. According to thy promises; according to the arrangements in thy word.

Let my supplication come before thee,.... The same with his "cry" in Psalm 119:169; only expressed by another word, signifying a petition for grace and favour, in an humble and submissive manner; which it is entreated might be received and accepted, as before;
deliver me according to thy word; of promise, such as that in Psalm 50:15; meaning from all troubles and afflictions; out of the hands of all his enemies, and from the power of sin, Satan, and the world; and from all fears of wrath, ruin, and destruction. Kimchi observes, that this is not to be understood of a deliverance of the body from distress, but of the soul from the stumbling block of sin.