I am weary of crying David, in seeking and calling upon God, when his affairs were in such a confused and desperate condition, exhibited an instance of rare and wonderful patience. He complains of having continued crying until he was exhausted and became hoarse, and all to no purpose. By the word weary, he does not mean that he gave up with prayer, as if he had cast from him all love to and delight in that exercise upon finding that it proved unavailing as a means of deliverance. He rather describes his untiring perseverance; and the same idea is expressed by his hoarse throat and failing eyes. [1] He certainly did not cry out before men from mere affectation, nor was this hoarseness contracted in the course of one day. We perceive, then, that although his bodily senses failed him, the vigor of his faith was by no means extinguished. When we reflect that David has spoken, as it were, out of the mouth of Christ, and, as it were, out of the mouth of all true saints who are the members of Christ, we ought not to think that any strange thing happens to us, if at any time we are so overwhelmed with death, as to be unable to discern the slightest hope of life. Yea, rather let us learn betimes, while God spares us, to meditate on this truth, and derive the aid which it is fitted to impart under calamity, that even in the most profound depths of adversity faith may hold us up, and, what is more, may elevate us to God; there being, as Paul testifies, (Romans 8:39) no height nor depth which can separate us from the infinite love of Him who swallows up all depths, yea, even hell itself.

Footnotes

1 - "My sight faileth me,' etc. This is said metaphorically, the metaphor being taken from the pain occasioned to the eyes when they are long and intently fixed upon the same point." -- Cresswell

I am weary of my crying - The word "crying" here does not mean weeping, or shedding tears, but calling upon God for help. He had grown weary; his strength had been exhausted in the act of calling upon God to assist him. See the notes at Psalm 6:6. This was an instance where one had called so long on God, and prayed so much and so earnestly, that his strength was gone. Compare Matthew 26:41.
My throat is dried - Or, "is parched up." The Hebrew word denotes to burn; to be enkindled; and then, to be inflamed. Here it means that by the excessive exertion of his voice, his throat had become parched, so that he could not speak.
Mine eyes fail - That is, become dim from exhaustion. I have looked so long in that one direction that the power of vision begins to fail, and I see nothing clearly. See the notes at Psalm 6:7. Compare Job 17:7; Psalm 31:9; Psalm 38:10.
While I wait for my God - That is, by continued "looking" to God. The word "wait" is not used here, nor is it generally in the Bible, as it is now with us, in the sense of looking for "future" interposition, or of doing nothing ourselves in expectation of what "may" occur; but it is used in the sense of looking to God alone; of exercising dependence on him; of seeking his aid. This is indeed connnected with the ordinary idea of abiding his will, but it is also an "active" state of mind - a state expressive of intense interest and desire. See the notes at Psalm 62:5.

I am weary of my crying - A pathetic description of the state of the poor captives for about seventy years.

I am weary of my crying: my throat is dried: mine (d) eyes fail while I wait for my God.
(d) Though his senses failed him, yet his faith was constant and encouraged him still to pray.

I am weary of my crying,.... In his distress; when, bearing the punishment both of loss and sense, he cried unto God; he prayed earnestly, with great intenseness and fervency of spirit; he offered supplications, with strong cryings and tears, insomuch that he calls it a roaring: and whereas there was a seeming delay of answer to his cries, he cried till he was weary of crying; and yet it is remarkable that his last cry was with a loud voice, which surprised the centurion; see Psalm 22:1;
my throat is dried; with crying, so that he was hoarse; or "burnt" (u); with inward heat of a fever, which usually attended persons crucified; see Psalm 22:15;
mine eyes fail while I wait for my God; God the Father was the God of Christ, as he was man; he prepared a body for him, and anointed his human nature with the Holy Spirit; he supported and upheld him: and as such Christ loved him, believed in him, prayed to him, and waited and looked for help and salvation from him; this being delayed, his eyes failed with intense looking about for it, as well as with grief and tears. Ainsworth observes, that failing of the eyes is one of the curses of the law, Leviticus 26:16, and it shows how in every thing Christ was made a curse for his people.
(u) "adustum", Montanus, Gejerus, Michaelis; so Ainsworth.

(Compare Psalm 6:6).
mine eyes fail--in watching (Psalm 119:82).