I lift my eyes to thee, who dwellest in the heavens. It is uncertain at what time, or even by what Prophet, this Psalm was composed. I do not think it probable that David was its author; because, when he bewails the persecutions which he suffered in the time of Saul, it is usual with him to inter-pose some particular references to himself. My opinion, then, rather is, that this form of prayer was composed for all the godly by some Prophet, either when the Jews were captives in Babylon, or when Antiochus Epiphanes exercised towards them the most relentless cruelty. Be this as it may, the Holy Spirit, by whose inspiration the Prophet delivered it to the people, calls upon us to have recourse to God, when -- ever wicked men unrighteously and proudly persecute, not one or two of the faithful only, but the whole body of the Church. Moreover, God is here expressly called the God who dwelleth in the heavens, not simply to teach his people to estimate the divine power as it deserves, but also that, when no hope of aid is left for them on earth, yea rather, when their condition is desperate, just as if they were laid in the grave, or as if they were lost in a labyrinth, they should then remember that the power of God remains in heaven in unimpaired and infinite perfection. Thus these words seem to contain a tacit contrast between the troubled and confused state of this world and God's heavenly kingdom, from whence he so manages and governs all things, that whenever it pleases him, he calms all the agitations of the world, comes to the rescue of the desperate and the despairing, restores light by dispelling darkness, and raises up such as were cast down and laid prostrate on the ground. This the Prophet confirms by the verb lift up; which intimates, that although all worldly resources fail us, we must raise our eyes upward to heaven, where God remains unchangeably the same, despite the mad impetuosity of men in turning all things here below upside down.

Unto thee - To God.
Lift I up mine eyes - In supplication and prayer. Nature prompts us to look up when we address God, as if he dwelt above us. It is the natural prompting of the heart that he must be the most exalted of all beings, dwelling above all. See Psalm 121:1.
O thou that dwellest in the heavens - Whose home - whose special home - is in heaven - above the sky. This is in accordance with the common feelings of people, and the common description of God in the Bible, though it is true also that God is everywhere. Compare Psalm 2:4; Psalm 11:4.

Unto thee lift I up mine eyes - We have no hope but in thee; our eyes look upward; we have expectation from thy mercy alone.

Unto thee lift I up mine eyes,.... Not only the eyes of his body, this being a prayer gesture; see Matthew 14:19; but the eyes of his mind and understanding, opened by the Spirit of God; particularly the eye of faith, by which he looked for and expected help and salvation from the Lord. The phrase is expressive of holy confidence in God, and a comfortable hope of receiving good things from him; as, on the contrary, when persons are ashamed and confounded with a sense of their sins, and the aggravations of them, and of their own unworthiness and vileness; and, on account of the same, almost out of all hope, cannot lift up their eyes to heaven, or their face before God, Ezra 9:6;
O thou that dwellest in the heavens; the heaven of heavens, the third heaven, the seat of angels and glorified saints; and though the Lord is everywhere, and fills heaven and earth with his presence, and cannot be contained any where; yet here is the more visible display of his glory; here he keeps his court; this is his palace, and here his throne is prepared, and on it he sits (d); so some render the word here; as the Judge of the whole earth, and takes a view of all men and their actions; and, as the God of nature and providence, governs and orders all things after his own will; and, as the God of grace, sits on a throne of grace, kindly inviting and encouraging his people to come unto him: and therefore the psalmist addresses him as such; see Ecclesiastes 5:2, Matthew 6:9. The Targum is,
"O thou that sittest on a throne of glory in heaven!''
(d) "sedens", Montanus, Gejerus; "qui sedes", Junius & Tremellius, Piscator, Cocceius, Michaelis; so Ainsworth.

Our Lord Jesus has taught us to look unto God in prayer as our Father in heaven. In every prayer a good man lifts up his soul to God; especially when in trouble. We desire mercy from him; we hope he will show us mercy, and we will continue waiting on him till it come. The eyes of a servant are to his master's directing hand, expecting that he will appoint him his work. And also to his supplying hand. Servants look to their master or their mistress for their portion of meat in due season. And to God we must look for daily bread, for grace sufficient; from him we must receive it thankfully. Where can we look for help but to our Master? And, further, to his protecting hand. If the servant is wronged and injured in his work, who should right him, but his master? And to his correcting hand. Whither should sinners turn but to him that smote them? They humble themselves under God's mighty hand. And lastly, to his rewarding hand. Hypocrites look to the world's hand, thence they have their reward; but true Christians look to God as their Master and their Rewarder. God's people find little mercy with men; but this is their comfort, that with the Lord there is mercy. Scorning and contempt have been, are, and are likely to be, the lot of God's people in this world. It is hard to bear; but the servants of God should not complain if they are treated as his beloved Son was. Let us then, when ready to faint under trials, look unto Jesus, and by faith and prayer cast ourselves upon the mercy of God.

An earnest and expecting prayer for divine aid in distress. (Psalm 123:1-4)
(Compare Psalm 121:1).
thou that dwellest--literally, "sittest as enthroned" (compare Psalm 2:4; Psalm 113:4-5).

The destinies of all men, and in particular of the church, are in the hand of the King who sits enthroned in the unapproachable glory of the heavens and rules over all things, and of the Judge who decides all things. Up to Him the poet raises his eyes, and to Him the church, together with which he may call Him "Jahve our God," just as the eyes of servants are directed towards the hand of their lord, the eyes of a maid towards the hand of her mistress; for this hand regulates the whole house, and they wait upon their winks and signs with most eager attention. Those of Israel are Jahve's servants, Israel the church is Jahve's maid. In His hand lies its future. At length He will take compassion on His own. Therefore its longing gaze goes forth towards Him, without being wearied, until He shall graciously turn its distress. With reference to the i of היּשׁבי, vid., on Psalm 113:1-9, Psalm 114:1-8. אדוניהם is their common lord; for since in the antitype the sovereign Lord is meant, it will be conceived of as plur. excellentiae, just as in general it occurs only rarely (Genesis 19:2, Genesis 19:18; Jeremiah 27:4) as an actual plural.