Let his children be fatherless - Hebrew, "his sons." This is what "always" occurs when a criminal who is a father is executed. It is one of the consequences of crime; and if the officer of justice does his duty, of course, the sons of such a man "must" be made fatherless. The prayer is, simply, that justice may be done, and all this is but an enumeration of what must follow from the proper execution of the laws.
And his wife a widow - This implies no malice against the wife, but may be consistent with the most tender compassion for her sufferings. It is simply one of the consequences which must follow from the punishment of a bad man. The enumeration of these things shows the enormity of the crime - just as the consequences which follow from the execution of a murderer are an illustration of the divine sense of the evil of the offence.

Let his children be fatherless, etc. - It is said that Judas was a married man, against whom this verse, as well as the preceding is supposed to be spoken; and that it was to support them that he stole from the bag in which the property of the apostles was put, and of which he was the treasurer.

Let his children be fatherless, and his wife a widow. This sometimes is the case of good men, who leave widows and fatherless children, whom the Lord shows mercy to; being the Father of the fatherless, and the Judge of the widow, Psalm 68:5, but sometimes it is threatened and comes as a judgment, when the Lord shows no mercy and favour to them, Exodus 22:24. And this is the case here, which very probably was literally fulfilled in Judas, who might have a wife and children; since it looks as if the other apostles had, and certain it is that one of them had a wife, even Peter, in the times of Christ; see 1-Corinthians 9:5. And this was verified in the people of the Jews; whom the Lord divorced from himself, and wrote a "loammi" upon them, and left them as orphans and fatherless, Hosea 1:9. This will never be the case of Christ's people, or the Christian church, John 14:18, though it will be of the antichristian one, Revelation 18:7.

Let his family share the punishment, his children be as wandering beggars to prowl in their desolate homes, a greedy and relentless creditor grasp his substance, his labor, or the fruit of it, enure to strangers and not his heirs, and his unprotected, fatherless children fall in want, so that his posterity shall utterly fail.