Persecuted Jesus - They opposed him; attempted to ruin his character; to destroy his popularity; and probably held him up before the people as a violator of the law of God. Instead of making inquiry whether he had not given proof that he was the Messiah, they "assumed" that he must be wrong, and ought to be punished. Thus every bigot and persecutor does in regard to those who differ from them.
To slay him - To put him to death. This they attempted to do because it was directed in the law of Moses, Exodus 31:15; Exodus 35:2. See Luke 6:7, Luke 6:11; Luke 13:14. We see here,
1. How full of enmity and how bloody was the purpose of the Jews, All that Jesus had done was to restore an infirm man to health - a thing which they would have done for their cattle Luke 6:7, and yet they sought. his life because he had done it for a sick "man."
2. Men are often extremely envious because good is done by others, especially if it is not done according to the way of their denomination or party.
3. Here was an instance of the common feelings of a hypocrite. He often covers his enmity against the power of religion by great zeal for the form of it. He hates and persecutes those who do good, who seek the conversion of sinners, who love revivals of religion and the spread of the gospel, because it is not according to some matter of form which has been established, and on which he supposes the whole safety of the church to hang. There was nothing that Jesus was more opposed to than hypocrisy, and nothing that he set himself more against than those who suppose all goodness to consist in "forms," and all piety in the "shibboleths" of a party.

And sought to slay him - This clause is omitted by BCDL, some others, and several ancient versions. Griesbach has left it out of the text; and Professor White says, certissime delenda: but it does not appear to me that it should be omitted. However, it was true of the Jews, whether the words were originally in the evangelist or not. For what cause did these persons seek to destroy our Lord? Because he had healed a poor man, who had been diseased thirty-eight years, and ordered him to carry home the couch on which he lay! How implacable must their malice have been! The spirit of religious persecution has always been the most fell and dangerous of all on this side perdition. Every other disposition appears to have its moderator; but this is wholly abandoned to the guidance of Satan, and has for its objects the men who know the truth, and who live to the glory of their God, and for the benefit of mankind. How strange that such should ever be objects of malice and hatred! But the Satanic nature in fallen man is ever opposed to whatever comes from God.

And therefore did the Jews persecute Jesus,.... With their tongues, reproaching and reviling him, as a sabbath breaker, a destroyer of the law, and a sinful wicked man:
and sought to slay him; either in a violent way, by setting the zealots, a sort of ruffians under the pretence of religion, upon him; or rather in a judicial way, summoning him before the sanhedrim, in order to condemn him to death for the breach of the sabbath, which by the law of Moses was punishable with death:
because he had done these things on the sabbath day; because he had cured the man of his disease, under which he had laboured eight and thirty years, and had ordered him to take up his bed, and walk home with it on his back on the sabbath day. This drew upon him their resentment to such a degree, that they not only persecuted him with their tongues, but sought to take away his life. Nothing would satisfy them but his blood.

because he had done these things on the sabbath day--What to these hypocritical religionists was the doing of the most glorious and beneficent miracles, compared with the atrocity of doing them on the sabbath day! Having given them this handle, on purpose to raise the first public controversy with them, and thus open a fitting opportunity of laying His claims before them, He rises at once to the whole height of them, in a statement which for grandeur and terseness exceeds almost anything that ever afterwards fell from Him, at least to His enemies.

The Jews persecute Jesus. The word is literally rendered "pursued Jesus." At once they hunted Jesus and attacked him. They did not at first seek to slay him. This is omitted in the Revision and does not appear in the old MSS. But the officials now come to Jesus to learn why he has done this act.