Now, therefore, cursed shalt thou be upon the earth, which hath opened her mouth and received the blood of thy brother at thy hand,

And now you are cursed from the earth, whose mouth is open to take your brother's blood from your hand;

Now, therefore, you will be cursed upon the land, which opened its mouth and received the blood of your brother at your hand.

nuc itaque maledictus eris e terra, quae aperuit os suum ut exciperet sanuinem fratris tui e manu tua.

And now art thou cursed from the earth. Cain, having been convicted of the crime, judgment is now pronounced against him. And first, God constitutes the earth the minister of his vengeance, as having been polluted by the impious and horrible parricide: as if he had said, Thou didst just now deny to me the murder which thou hast committed, but the senseless earth itself will demand thy punishment.' He does this, however, to aggravate the enormity of the crime, as if a kind of contagion flowed from it even to the earth, for which the execution of punishment was required. The imagination of some, that cruelty is here ascribed to the earth, as if God compared it to a wild beast, which had drunk up the blood of Abel, is far from the true meaning. Clemency is rather, in my judgment, by personification, [1] imputed to it; because, in abhorrence of the pollution, it had opened its mouth to cover the blood which had been shed by a brother's hand. Most detestable is the cruelty of this man, who does not shrink from pouring forth his neighbor's blood, of which the bosom of the earth becomes the receptacle. Yet we must not here imagine any miracle, as if the blood had been absorbed by any unusual opening of the earth; but the speech is figurative, signifying that there was more humanity in the earth than in man himself. Moreover, they who think that, because Cain is now cursed in stronger words than Adam had previously been, God had dealt more gently with the first man, from a design to spare the human race; have some color for their opinion. Adam heard the words, "Cursed is the ground for thy sake:" but now the shaft of divine vengeance vibrates against, and transfixes the person of Cain. The opinion of others, that temporal punishment is intended, because it is said, Thou art cursed from the "earth," rather than from "heaven," lest the posterity of Cain, being cut off from the hope of salvation, should rush the more boldly on their own damnation, seems to me not sufficiently confirmed. I rather interpret the passage thus: Judgment was committed to the earth, in order that Cain might understand that his judge had not to be summoned from a distance; that there was no need for an angel to descend from heaven, since the earth voluntarily offered itself as the avenger.

Footnotes

1 - "Kata prosopopoiian"

And now [art] thou cursed (k) from the earth, which hath opened her mouth to receive thy brother's blood from thy hand;
(k) The earth will be a witness against you, which mercifully received the blood you most cruelly shed.

And now art thou cursed from the earth,.... From receiving benefit by it, and enjoying the fruits of it as before, and from having a settled dwelling in it, as is afterwards explained:
which hath opened her mouth to receive thy brother's blood from thy hand; the blood of his brother, which was shed by his own hand, was received and sucked into the earth, where it was spilt, through the pores of it, and drank up and covered, so as not to be seen; in which it was as it were more humane to Abel, and as it were more ashamed of the crime, and shuddered more, and expressed more horror at it, than Cain.

now art thou cursed from the earth--a curse superadded to the general one denounced on the ground for Adam's sin.

"And now (sc., because thou hast done this) be cursed from the earth." From: i.e., either away from the earth, driven forth so that it shall no longer afford a quiet resting-place (Gerlach, Delitzsch, etc.), or out of the earth, through its withdrawing its strength, and thus securing the fulfilment of perpetual wandering (Baumgarten, etc.). It is difficult to choose between the two; but the clause, "which hath opened her mouth," etc. seems rather to favour the latter. Because the earth has been compelled to drink innocent blood, it rebels against the murderer, and when he tills it, withdraws its strength, so that the soil yields no produce; just as the land of Canaan is said to have spued out the Canaanites, on account of their abominations (Leviticus 18:28). In any case, the idea that "the soil, through drinking innocent blood, became an accomplice in the sin of murder," has no biblical support, and is not confirmed by Isaiah 26:21 or Numbers 35:33. The suffering of irrational creatures through the sin of man is very different from their participating in his sin. "A fugitive and vagabond (ונד נע, i.e., banished and homeless) shalt thou be in the earth." Cain is so affected by this curse, that his obduracy is turned into despair, "My sin," he says in Genesis 4:13, "is greater than can be borne." עון נשׁא signifies to take away and bear sin or guilt, and is used with reference both to God and man. God takes guilt away by forgiving it (Exodus 34:7); man carries it away and bears it, by enduring its punishment (cf. Numbers 5:31). Luther, following the ancient versions, has adopted the first meaning; but the context sustains the second: for Cain afterwards complains, not of the greatness of the sin, but only of the severity of the punishment. "Behold, Thou hast driven me out this day from the face of the earth, and from Thy face shall I be hid;...and it shall come to pass that every one that findeth me shall slay me." The adamah, from the face of which the curse of Jehovah had driven Cain, was Eden (cf. Genesis 4:16), where he had carried on his agricultural pursuits, and where God had revealed His face, i.e., His presence, to the men after their expulsion from the garden; so that henceforth Cain had to wander about upon the wide world, homeless and far from the presence of God, and was afraid lest any one who found him might slay him. By "every one that findeth me" we are not to understand omnis creatura, as though Cain had excited the hostility of all creatures, but every man; not in the sense, however, of such as existed apart from the family of Adam, but such as were aware of his crime, and knew him to be a murderer. For Cain is evidently afraid of revenge on the part of relatives of the slain, that is to say, of descendants of Adam, who were either already in existence, or yet to be born. Though Adam might not at this time have had "many grandsons and great-grandson," yet according to Genesis 4:17 and Genesis 5:4, he had undoubtedly other children, who might increase in number, and sooner or later might avenge Abel's death. For, that blood shed demands blood in return, "is a principle of equity written in the heart of every man; and that Cain should see that earth full of avengers is just like a murderer, who sees avenging spirits (Ἐρινύες) ready to torture him on every hand."

And now art thou cursed from the earth - 1. He is cursed, separated to all evil, laid under the wrath of God, as it is revealed from heaven against all ungodliness and unrighteousness of men. 2. He is cursed from the earth. Thence the cry came up to God, thence the curse came up to Cain. God could have taken vengeance by an immediate stroke from heaven: but he chose to make the earth the avenger of blood; to continue him upon the earth, and not presently to cut him off; and yet to make even that his curse. That part of it which fell to his share, and which he had the occupation of, was made unfruitful, by the blood of Abel.
Besides, A fugitive and a vagabond shalt thou be in the earth. By this he was here condemned, to perpetual disgrace and reproach, and to perpetual disquietment and horror in his own mind. His own guilty conscience should haunt him where ever he went.
Now to justify his complaint, Observe his descants upon the sentence. He sees himself excluded by it from the favour of his God; and concludes, that being cursed, he was hid from God's face, and that is indeed the true nature of God's curse; damned sinners find it so, to whom it is said, Depart from me ye cursed. Those are cursed indeed that are for ever shut out from God's love and care, and from all hopes of his grace. He sees himself expelled from all the comforts of this life; and concludes, Genesis 4:14. Thou hast driven me out this day from the face of the earth - As good have no place on earth as not have a settled place. Better rest in the grave than not rest at all. And from thy face shall I be hid - Shut out of the church, not admitted to come with the sons of God to present himself before the Lord. And it shall come to pass that every one that finds me shall slay me - Wherever he wanders he goes in peril of his life. There were none alive but his near relations, yet even of them he is justly afraid, who had himself been so barbarous to his own brother.