With the Church that is in their house A magnificent eulogium, inasmuch as the name of the Church is applied to a single family! At the same time it is befitting, that all the families of the pious should be regulated in such a manner as to be so many little Churches. As to the term Congregation, which Erasmus has used in preference, it is foreign to Paul's design; for it was not his intention to designate a crowd of persons by a mere common term, but to speak in honorable terms of the management of a Christian household. His saluting them in the name of Aquila and Priscilla, confirms what I have noticed above -- that the Epistle was written at Ephesus, not at Philippi. For Luke informs us, that they remained at Ephesus, when Paul went elsewhere. (Acts 18:19.)

The churches of Asia - The word "Asia" in the New Testament usually denotes Asia Minor in general; see the note on Acts 2:9. It was sometimes used in a more limited sense, to denote the region around Ephesus, and of which Ephesus was the center and capital; see note, Acts 16:6. This is the region undoubtedly which is intended here.
Salute you - Greet you; send respectful and affectionate Christian regards; see the note at Romans 16:3.
Aquila and Priscilla - See the note on Acts 18:26.
Much in the Lord - With affectionate Christian salutations; or as Christians. Wishing the blessing and favor of the Lord.
With the church that is in their house - See the note at Romans 16:5.

The Churches of Asia salute you - i.e. The Churches in Asia Minor. Ephesus was in this Asia, and it is clear from this that the apostle was not at Philippi; had he been at Philippi, as the subscription states, he would have said, The Churches of Macedonia, not the Churches of Asia, salute you. How these places lay, in reference to each other, the reader will at once perceive by consulting the map in Acts.
Aquila and Priscilla - Of these eminent persons we have heard before: see Acts 18:2, Acts 18:18, Acts 18:26; and Romans 16:3.
With the Church that is in their house - That is, the company of believers who generally worshipped there. There were no churches or chapels at that time built; and the assemblies of Christians were necessarily held in private houses. It appears that Aquila and Priscilla devoted their house to this purpose. The house of Philemon was of the same kind; Plm 1:2. So was likewise the house of Nymphas, Colossians 4:15. See the note on Romans 16:5.

The churches of Asia salute you,.... The Syriac version renders it, "all" the churches. This shows, that this epistle was not written from Philippi, as the subscription to it attests, for then he would rather have said; the churches of Macedonia salute you, but at Ephesus, where he now was; see 1-Corinthians 16:8; and this is the more confirmed, by the following salutation of Aquila and Priscilla, who it is plain from Acts 18:18, were with the apostle at Ephesus:
Aquila and Priscilla salute you much in the Lord; Aquila was a Jew of Pontus, and Priscilla was his wife, who came from Italy, all Jews being obliged to depart from Rome, by the order of Claudius Caesar. These came to Corinth, where they met with the apostle; and being of the same occupation, stayed and wrought with him; and when he went from thence to Ephesus, accompanied him thither; see Acts 18:3; wherefore having personal knowledge of the members of this church, through their stay with the apostle there, for the space of a year and a half, send their Christian salutations to them, with great affection and respect:
with the church that is in their house: their family consisting of believers, and being kept in such good decorum, and employed daily in singing, praying, expounding, and conferring together about divine things, looked like a little church; and it may be that at certain times the principal members of the church at Ephesus met in their house for religious worship, and to consider and debate about the affairs of the church; and very likely as they were of the same occupation with the apostle, he himself dwelt here; and which might be the more an occasion of the church assembling here at times; and the Vulgate Latin version adds, "with whom also I lodge".

Christianity by no means destroys civility. Religion should promote a courteous and obliging temper towards all. Those give a false idea of religion, and reproach it, who would take encouragement from it to be sour and morose. And Christian salutations are not mere empty compliments; but are real expressions of good-will to others, and commend them to the Divine grace and blessing. Every Christian family should be as a Christian church. Wherever two or three are gathered together in the name of Christ, and he is among them, there is a church. Here is a solemn warning. Many who have Christ's name much in their mouths, have no true love to him in their hearts. None love him in truth, who do not love his laws, and keep his commandments. Many are Christians in name, who do not love Christ Jesus the Lord in sincerity. Such are separated from the people of God, and the favour of God. Those who love not the Lord Jesus Christ, must perish without remedy. Let us not rest in any religious profession where there is not the love of Christ, earnest desires for his salvation, gratitude for his mercies, and obedience to his commandments. The grace of our Lord Jesus Christ has in it all that is good, for time and for eternity. To wish that our friends may have this grace with them, is wishing them the utmost good. And this we should wish all our friends and brethren in Christ. We can wish them nothing greater, and we should wish them nothing less. True Christianity makes us wish those whom we love, the blessings of both worlds; this is meant in wishing the grace of Christ to be with them. The apostle had dealt plainly with the Corinthians, and told them of their faults with just severity; but he parts in love, and with a solemn profession of his love to them for Christ's sake. May our love be with all who are in Christ Jesus. Let us try whether all things appear worthless to us, when compared with Christ and his righteousness. Do we allow ourselves in any known sin, or in the neglect of any known duty? By such inquiries, faithfully made, we may judge of the state of our souls.

Asia--not all Asia Minor, but Lydian Asia only, of which Ephesus was the capital.
much--with especial affection.
Aquila . . . Priscilla--(Compare Acts 18:2; Romans 16:3-4). Originally driven out of Italy by Claudius, they had come to Corinth (whence their salutation of the Corinthians is appropriate here), and then had removed with Paul from Corinth to Ephesus (Acts 18:2, Acts 18:18-19, Romans 16:3, Romans 16:5). A pattern to Christian husbands and wives. Their Christian self-devoting love appears wherever they were (Romans 16:3-4). Even the gifted Apollos, so highly admired at Corinth, owed much of his knowledge to them (Acts 18:24-26). In 1-Corinthians 16:20, "All the brethren" (that is, the whole Church) seem to be distinguished from "the church that is in their house," which was but a partial and private assembly out of the general Church at Corinth. NEANDER thinks Romans 16:23 refers to "the whole Church" meeting at the house of Gaius (compare Colossians 4:15). "Synagogue" implies an assembly in general, without reference to the character or motives of its members. "Church," like the Hebrew Kahal, implies an assembly legally convened; as, for instance, the Jews met as a body politic to receive the law (hence Stephen calls it "the Church in the wilderness," Acts 7:38), and having a legal bond of union. Christ's followers when dispersed from one another cease to be a congregation (synagogue), but still are a Church, having the common bond of union to the same Head by the same faith and hope [VITRINGA, Synagogue and Temple]. From this we may explain Paul's entering "into every house and haling men and women": he would in searching for Christians go to their several "houses"' of prayer.
in the Lord--They pray for all blessings on you from the Lord, the source of every good [GROTIUS]. ALFORD explains, "in a Christian manner," as mindful of your common Lord. "In the Lord" seems to me to refer to their union together in Christ, their prayers for one another's good being in virtue of that union.

Aquila and Priscilla had formerly made some abode at Corinth, and there St. Paul's acquaintance with them began, Acts 18:1-2.