Salute the brethren which are in Laodicea - Notes, Colossians 2:1.
And Nymphas - This person is nowhere else mentioned, and nothing more is known of him.
And the church which is in his house - Notes, Romans 16:5.

Salute - Nymphas, and the Church - in his house - This person, and his whole family, which probably was very numerous, appear to have received the Gospel; and it seems that, for their benefit and that of his neighbors, he had opened his house for the worship of God. In those primitive times there were no consecrated places, for it was supposed that the simple setting apart of any place for the worship of God was a sufficient consecration. See of those domestic churches, Romans 16:5 (note); 1-Corinthians 16:19 (note)

Salute the brethren which are in Laodicea,.... Where there was a church mentioned in the following verse, of which see on Gill Revelation 2:10.
And Nymphas; which some, unskilful in the Greek language, have took for a woman; whereas it is the name of a man, as the following words show; and is a contraction of Nymphios, or Nymphidios, or Nymphodoros:
and the church which is in his house. This man seems to have been an inhabitant of Laodicea, and that the church there met at his house to worship God, to pray unto him, sing his praise, hear his word, and attend on all ordinances: or his own family was brought up so strictly to the observance of these things, that they looked like a little church of themselves.

Nymphas--of Laodicea.
church . . . in his house--So old manuscripts and Vulgate read. The oldest read, "THEIR house"; and one manuscript, "HER house," which makes Nymphas a woman.

Nymphas - Probably an eminent Christian at Laodicea.