And he opened his mouth in blasphemy against God, to blaspheme his name, and his tabernacle, and them that dwell in heaven.

And he opened his mouth for blasphemies against God, to blaspheme his name, and his tabernacle, even them that dwell in the heaven.

And it opened its mouth for blasphemies against God, to blaspheme his name and his tabernacle, and those who have their tabernacle in the heaven.

and it did open its mouth for evil-speaking toward God, to speak evil of His name, and of His tabernacle, and of those who in the heaven tabernacle,

And he opened his mouth to utter blasphemies against God, to speak evil of His name and of His dwelling-place - that is to say, of those who dwell in Heaven.

And his mouth was open to say evil against God, and against his name and his Tent, even against those who are in heaven.

He opened his mouth for blasphemies against God, to blaspheme his name, and his dwelling, those who dwell in heaven.

It opened its mouth only to blaspheme God, to blaspheme his name and his tent – those who live in his tent in heaven.

And he opened his mouth in blasphemy against God, to blaspheme his name - By his own arrogant claims; by his assumed authority in matters of conscience; by setting aside the divine authority; and by impious declarations in derogation of the divine claims. See the notes on Revelation 13:1.
And his tabernacle - Literally, his "tent" - σκηνὴν skēnēn. This is the word which is commonly applied to the sacred tent or tabernacle among the Hebrews, in which the ark was kept, and which was the seat of the Jewish worship before the building of the temple. It is thus used to denote a place of worship, considered as the dwelling-place of God, and is in this sense applied to heaven, Hebrews 8:2; Hebrews 9:11; Revelation 15:5. It seems to be used here in a general sense to denote the place where God was worshipped; and the meaning is, that there would be a course of conduct in regard to the true church - the dwelling-place of God on the earth - which could properly be regarded as blasphemy. Let anyone remember the anathemas and excommunications uttered against the Waldenses and Albigenses, and those of kindred spirit that appeared in the long period of the papal rule, and he will find no difficulty in perceiving a complete fulfillment of all that is here said.
And them that dwell in heaven - The true worshippers; the members of the true church, represented as dwelling in this holy tabernacle. No one acquainted with the reproaches cast on the devoted and sincere followers of the Saviour during the dark periods of the papal rule can fail to see that there was in that a complete fulfillment of all that is here predicted.

And he opened his mouth in blasphemy against God, to blaspheme his name - The Latin empire is here represented as a blasphemous power in three respects. First, he blasphemes the name of God. This has been most notoriously the case with the different popish princes, who continually blaspheme the sacred names of God by using them in their idolatrous worship. The mouth of blasphemy against God cannot be more evident than in the following impious words which form a part of the Golden Bull published by Charles IV. in January, 1356: "But thou, envy, how often hast thou attempted to ruin by division the Christian empire, which God hath founded upon the three cardinal virtues, faith, hope, and charity, as upon a holy and indivisible Trinity, vomiting the old venom of discord among the seven electors, who are the pillars and seven principal members of the holy empire; by the brightness of whom the holy empire ought to be illuminated as by seven torches, the light of which is reinforced by the seven gifts of the Holy Spirit!"
And his tabernacle - Tabernacle is any kind of dwelling place, and in an eminent sense among the Jews was a kind of tent to take up and down as occasion required, which was as it were the palace of the Most High, the dwelling of the God of Israel. It was divided into two partitions, one called the holy place, and the other the most holy place, in the latter of which, before the building of the temple, the ark of the covenant was kept, which was a symbol of God's gracious presence with the Jewish Church. All this the author of the Epistle to the Hebrews, in the eighth and ninth chapters, explains to prefigure the human nature of Christ. The beast's blasphemy of the tabernacle of God is, therefore, as Dr. More and others properly observe, his impious doctrine of transubstantiation, in which it is most blasphemously asserted that the substance of the bread and wine in the sacrament is literally converted by the consecration of the priest, into the very body and blood of Jesus Christ! This doctrine was first advanced among the Latins in the tenth century; and in 1215, fully received as an article of the Roman Catholic faith. It is for the pages of ecclesiastical history to record the incredible numbers which have been martyred by the papists for their non-reception of this most unscriptural and antichristian doctrine.
And them that dwell in heaven - By heaven is here meant the throne of God, and not the throne of the beast, because it is against God the beast blasphemes. This must therefore allude to his impious adoration of the saints and angels, whose residence is in heaven. He blasphemes against God by paying that adoration to the celestial inhabitants which belongs to God alone. That this sort of worship has been and still is kept up among the Roman Catholics, their mass book is a sufficient evidence.

And he opened his mouth in blasphemy against God, to blaspheme his name, (11) and his tabernacle, (12) and them that dwell in heaven.
(11) That is, the holy Church, the true house of the living God.
(12) That is, the godly who as a group hid themselves from his cruelty. For this bloody beast charged those holy souls falsely with innumerable accusations for the name of Christ as we read in Justin Martyr, Tertullian, Arnobius, Minutius, Eusebius, Augustine and others: whose example the latter times followed most diligently, in destroying the flock of Christ: and we in our own memory have found by experience, to our incredible grief. Concerning heaven, see in (Revelation 11:12)

And he opened his mouth in blasphemy against God,.... By sitting as God in the temple of God, showing himself that he is God; by suffering himself to be called by the name of God, God on earth, Lord God the pope, and to be worshipped as God; and by assuming infallibility, giving out that he cannot err, which only belongs to the God of truth; and by his idolatrous practices commanded by him, as the worshipping of idols of gold, silver, wood, and stone, which is in Scripture called blaspheming God, Isaiah 65:7; see Daniel 11:36.
To blaspheme his name; his authority, by arrogating to himself all power in heaven, earth, and hell; by taking upon him to bind and loose the consciences of men, and to dispense with the laws of God, and make them void by his own traditions; and to dispose of the kingdoms of this world, by removing kings, and setting up kings at pleasure, which is the prerogative of the King of kings; and by pretending; to forgive sin, which none but God can do; and by granting indulgences, pardons, &c. Moreover, by the name of God may be meant the Scriptures, which are the means by which God reveals and makes known himself; and these the man of sin blasphemes, by making them a nose of wax, by imposing on them what senses he pleases; by assuming a right of being the sole interpreter of them, and the judge of all controversies; and by setting up his own unwritten traditions upon an equal foot with them, and above them, and by denying the common people the use of them, in their own language; and particularly the Gospel, which is sometimes called the name of the Lord, Acts 9:15, may be intended, which is sadly blasphemed, and evil spoken of by antichrist; as the doctrines of justification by Christ's righteousness, of peace and pardon by his blood, and atonement by his sacrifice, through the antichristian notions of merit, works of supererogation, pardons, penance, purgatory, and the like:
and his tabernacle; meaning either the human nature of Christ, which God pitched, and not man, the temple of his body, in which the Godhead dwells bodily, and where the eternal Word dwelt, or tabernacled among men; this is blasphemed by pretending to transubstantiate, the bread and wine in the supper of the Lord into the very body and blood of Christ, and to offer him up again in the sacrifice of the Mass, every time that blasphemous piece of service is performed: or else the church of God, which is the temple of the living God, where he chooses, desires, and delights to dwell; this is blasphemed by antichrist, by sitting in it as if he was God; asserting himself to be the head of the church which solely belongs to Christ; taking upon him to coin new doctrines, and make new laws and orders, and impose them on it, and to change and alter the ordinances and discipline of it as he pleases; and by persecuting and destroying all such who will not submit to his decrees and prescripts: or else heaven itself, the habitation of God, and where his throne is, may be designed, which the pope blasphemously affirms to have the keys of; and that he can open and shut it, let persons into it, or exclude front it, at pleasure; and that he can dispose of it, and sell it for money, and make and canonize new saints in it, as often as he thinks fit.
And them that dwell in heaven; either saints below, members of a Gospel church, who are born from above, are partakers of the heavenly calling, and whose conversation is in heaven, who are by antichrist stigmatized and persecuted as schismatics and heretics; or rather angels and saints departed, who are in heaven, and dwell there, and who are worshipped and prayed to as Mediators and intercessors, whose names are used in a very ridiculous and blasphemous manner, to their great dishonour and reproach, as well as to the injury of Christ, the only Mediator between God and men.

opened . . . mouth--The usual formula in the case of a set speech, or series of speeches. Revelation 13:6-7 expand Revelation 13:5.
blasphemy--So B and ANDREAS. A and C read "blasphemies."
and them--So Vulgate, Coptic, ANDREAS, and PRIMASIUS read. A and C omit "and": "them that dwell (literally, 'tabernacle') in heaven," mean not only angels and the departed souls of the righteous, but believers on earth who have their citizenship in heaven, and whose true life is hidden from the Antichristian persecutor in the secret of God's tabernacle. See on Revelation 12:12; John 3:7.