Turn away mine eyes. By these words we are taught that all our senses are so filled with vanity, that, until refined and rectified, their alienation from the pursuit of righteousness is no matter of surprise. In the former verse he informed us of the reigning of that depravity in the hearts of men, which he now says reaches also to the outward senses. "The disease of covetousness not only lurks in our hearts, but spreads over every part, so that neither eyes, ears, feet, nor hands, have escaped its baneful influence; in a word, nothing is exempted from corruption." And we know, assuredly, that the guilt of original sin is not confined to one faculty of man only; it pervades his whole constitution. If our eyes must be turned away from vanity by the special grace of God, it follows, that, as soon as they are opened, they are eagerly set on the impostures of Satan, by which they are beset on all sides. If Satan only laid snares for us, and were we possessed of sufficient prudence to guard against his deceits, it could not, with propriety, be said that God turned away our eyes from vanity; but, as they are naturally set upon sinful allurements, there is need for their being withdrawn from them. As often, then, as we open our eyes, we must not forget that two gates are opened for the devil to enter our hearts, unless God guard us by his Holy Spirit. The remarks which he makes, in reference to the eyes, are equally applicable to the other senses, inasmuch as he again employs that figure of speech, by which a part is taken for the whole. The other clause of the verse corresponds well with the meaning here given. Others may propose different interpretations; I think, however, the following is the most natural: Lord, as the whole life of mankind is accursed, so long as they employ their powers in committing sin, grant that the power which I possess may aspire after nothing except the righteousness which thou appointest us. The better to manifest this, we must lay it down as a first principle, that seeing, hearing, walking, and feeling, are God's precious gifts; that our understandings and will, with which we are furnished, are a still more valuable gift; and, after all, there is no look of the eyes, no motion of the senses, no thought of the mind, unmingled with vice and depravity. Such being the case, the prophet, with good reason, surrenders himself entirely to God, for the mortification of the flesh, that he might begin to live anew.

Turn away mine eyes from beholding vanity - Vain things; wicked things; things which would be likely to lead me astray from what is real and true. Compare Isaiah 33:15; Job 31:1. Margin, here, as in Hebrew, "make to pass." Make my eyes to pass rapidly from such objects, that I may not look at them, may not contemplate them, may not dwell upon them. There is danger in looking on sin steadily; in surveying its features; in returning to contemplate it. An ugly object loses much of its deformity when we look often upon it; and this is a benevolent law, lest we should be miserable when we are under a necessity of looking on it. Sin follows this general law, and is to be avoided altogether, even in its contemplation, if we would be safe. A man should be thankful in this world that he has eyelids; and as he can close his eyes, so he should often do it.
And quicken thou me in thy way - Endow me with life, energy, vigor, that I may walk in thy way.

From beholding vanity - An idol, worldly pleasure, beauty, finery; any thing that is vain, empty, or transitory. Let me not behold it; let me not dwell upon it. Let me remember Achan: he saw, - he coveted, - he took, - he hid his theft, and was slain for his sin.

Turn away mine (d) eyes from beholding vanity; [and] quicken thou me in thy way.
(d) Meaning, all his senses.

Turn away mine eyes from beholding vanity,.... As the things of this world, the riches, honours, and pleasures of it, which are all vanity and vexation of spirit; and yet these catch the eye, and allure the heart: and all false doctrines, glided over with the specious pretence of truth; and all false worship and superstition, set off with pomp and pageantry, with which the eyes of the body or the eyes of the mind are taken, and by which the heart is ensnared; and therefore it is desirable to have the eyes turned away from such objects unto better;
and quicken thou me in thy way; so as to walk and even run in the path of truth, in the way of true religion and godliness; and, instead of looking upon vanity, press towards the mark for the prize; keep Christ in view, while running the race; and look to things unseen, and not things that are seen; and set the affections on things above, and serve the Lord fervently; all which is done when God quickens the hearts of his people, and the graces of his Spirit in them.

Turn away mine eyes--literally, "Make my eyes to pass, not noticing evil."
vanity--literally, "falsehood;" all other objects of trust than God; idols, human power, &c. (Psalm 31:6; Psalm 40:4; Psalm 60:11; Psalm 62:9).
quicken . . . in thy way--make me with living energy to pursue the way marked out by Thee. Revive me from the death of spiritual helplessness (Psalm 119:17, Psalm 119:25, Psalm 119:40, Psalm 119:50; Psalm 116:3).

Vanity - The vain things of this present world, such as riches, honours, pleasures: from beholding them, with desire or affection. Quicken - Make me lively, vigorous and fervent in thy service.