He sendeth his word. Again, in saying that they are delivered from destruction, the prophet shows that he is here alluding to those diseases which, in the opinion of men, are incurable, and from which few are delivered. Besides, he contrasts God's assistance with all the remedies which are in the power of man to apply; as if he should say, that their disease having baffled the skill of earthly physicians, their recovery has been entirely owing to the exertion of God's power. It is proper also to notice the manner in which their recovery is effected; God has but to will it, or to speak the word, and instantly all diseases, and even death itself, are expelled. I do not regard this as exclusively referring to the faithful, as many expositors do. I own, indeed, that it is of comparatively little consequence to us to be the subjects of bodily care, if our souls still remain unsanctified by the word of God; and hence it is the intention of the prophet that we consider the mercy of God as extending to the evil and unthankful. The meaning of the passage, therefore, is, that diseases neither come upon us by chance, nor are to be ascribed to natural causes alone, but are to be viewed as God's messengers executing his commands; so that we must believe that the same person that sent them can easily remove them, and for this purpose he has only to speak the word. And since we now perceive the drift of the passage, we ought to attend to the very appropriate analogy contained in it. Corporeal maladies are not removed except by the word or command of God, much less are men's souls restored to the enjoyment of spiritual life, except this word be apprehended by faith. And let them sacrifice This clause is subjoined by way of explanation, the more strongly to express how God is robbed of his due, if in the matter of sacrifice his providence be not recognised. Even nature itself teaches that some kind of homage and reverence is due to God; this is acknowledged by the heathens themselves, who have no other instructor than nature. We know too, that the practice of offering sacrifices has obtained among all nations; and doubtless it was by the observance of this ritual, that God designed to preserve in the human family some sense of piety and religion. To acknowledge the bounty and beneficence of God, is the most acceptable sacrifice which can be presented to him; to this subject, therefore, the prophet intends to recall the attention of the insensate and indifferent portion of men. I do not deny that there may be also an allusion to the ceremonial law; but inasmuch as in the world at large sacrifices formed part of the religious exercises, he charges those with ingratitude, who, after having escaped from some imminent peril, forget to celebrate the praises of their Great Deliverer.

He sent his word, and healed them - He did it by a word; it was necessary for him merely to give a command, and the disease left them. So it was in the life of the Saviour, who often healed the sick by a "word" Matthew 8:8; Luke 7:7; and so now restoration from disease often seems to be accomplished as if some word had been spoken by one who had power, commanding the disease to depart. In all cases, also, whatever means may be used, healing power comes from God, and is under his control. Compare Psalm 30:2.
And delivered them from their destructions - From what would have destroyed them, if it had not been checked and removed.

He sent his word, and healed them - He spoke: "Be thou clean, be thou whole;" and immediately the disease departed; and thus they were delivered from the destructions that awaited them.

(h) He sent his word, and healed them, and delivered [them] from their (i) destructions.
(h) By healing them he declares his good will toward them.
(i) Meaning their diseases, which had almost brought them to the grave and corruption.

He sent his word, and healed them,.... It was his will and pleasure they should be healed, and accordingly they were; he issued his orders for the removal of the affliction, and it was done; diseases are his servants, which come and go at his command; so Christ, in the days of his flesh, healed by speaking a word, Matthew 8:3. This is true of Christ the essential Word, who was sent in the fulness of time, and was made flesh and dwelt among men, and went about healing all manner of diseases among the people; and who is also the physician of souls who came with healing in his wings; that is, with pardon of sin, for which his blood was shed: he is the only physician, the skilful, universal, and infallible one, and does all freely, and in a most marvellous manner, by his stripes, blood and wounds, and by an application of these to diseased persons sensible of their case. It may also be applied to the word of the Gospel; the law is the means of wounding, it is the killing letter; the Gospel is the means of healing, the doctrines of it are the leaves of the tree of life, which are for the healing of the nations; it is the doctrine of remission of sins by the blood of Christ, and by it Christ speaks peace and pardon to wounded consciences.
And delivered them from their destructions; from the destruction of the body, of the beauty and strength of it by diseases; restoring to health is a redeeming of the life from destruction; from the grave, the pit of corruption and destruction, so called because in it bodies corrupt, putrefy, and are destroyed by worms; and such who are savingly convinced of sin, and blessed with pardoning grace and mercy, are delivered from the everlasting destruction of body and soul in hell.

sent his word--that is, put forth His power.
their destructions--that is, that which threatened them. To the chorus is added the mode of giving thanks, by a sacrifice and joyful singing (Psalm 50:14).

Word - His command, or blessing.