Go in peace, and be delivered from thy scourge. From this exhortation we infer that the benefit which she had obtained was fully ratified, when she heard from the lips of Christ what she had already learned from experience: for we do not truly, or with a safe conscience, enjoy God's benefits in any other way than by possessing them as contained in the treasury of his promises.

Daughter - A word of kindness, tending to inspire confidence and to dissipate her fears.
Be whole - That is, continue to be whole, for she was already cured.
Of thy plague - Thy disease; literally, thy "scourge." So a word from Jesus heals the moral malady of the sinner.

Be whole of thy plague - Rather, continue whole, not, be whole, for she was already healed: but this contains a promise, necessary to her encouragement, that her disorder should afflict her no more.

And he said unto her, daughter,.... Instead of reproving her, or showing any anger, or resentment at her, as she feared, he speaks to her in a very soft, kind, and tender manner, and called her "daughter", which was not only an expression of affection and civility, this being an affable, courteous way of speaking used by the Jews; but might signify her spiritual relation through him, being a child of God by adopting grace. She was a daughter of Abraham by natural descent, as was the woman bound by Satan eighteen years, Luke 13:16 and so she was likewise in a spiritual sense, being one that walked in the steps of his faith, believing in hope against hope; and she was also a daughter of the Lord God Almighty, as her faith showed her to be, Galatians 3:26, and to this our Lord may chiefly refer; she was one of those that were predestinated to the adoption of children, and were given to Christ as such; and who are evidentially the children of God by faith in him: and to have a testimony of adoption from the Spirit of God, and from the mouth of Christ himself, as this woman had; how great a blessing is it!
thy faith hath made thee whole: through faith in Christ she received the cure from him; for it was not her act of faith that either merited, or procured it, but his power, and he himself the object of her faith that effected it: though he is pleased to take no further notice of the virtue that went out from him; but commends her faith, for her further and future encouragement in the exercise of it, and for the encouragement of others to believe in him. In the Greek text it is, "thy faith hath saved thee"; both from her bodily disease, and from her sins: not that there is such an intrinsic virtue in faith as to deliver from either; for certain it is, that it was not virtue that went out of her faith, but virtue which went out from Christ, that cured her of her issue; though faith was the means of drawing it out; or it was that, through which, virtue from Christ exerted itself, and produced such an effect: and it is as certain, that not faith, but Christ, is the author and cause of spiritual salvation: faith looks to Christ for salvation, and receives every blessing of it from him, as righteousness, peace, pardon, adoption, and eternal life; so that believers are saved by grace, through faith; through the exercise of that grace they have the joy, and comfort Of salvation now; and through it they are kept, by the power of God, unto the full possession of it hereafter.
Go in peace; to thine house; all health and happiness attend thee; let no uneasy thought, about what has passed, dwell on thy mind; be joyful and thankful for the mercy received, and never fear, or dread, a return of the disorder. Peace is the effect of faith in Christ, of pardon through his blood, and salvation in him; true, spiritual, solid peace is enjoyed in a way of believing; it is the fruit of a view of interest in justification by faith in Christ's righteousness; and nothing more effectually produces and secures it than a sense of, all spiritual diseases being healed, or an application of pardoning grace and mercy, through the blood of Christ; which itself speaks better things than that of Abel, even pardon, and so peace: such who are blessed in this manner, and walk under a view and sense of these things, go in peace all their days, and at last enter into peace, even into the joy of their Lord.
And be whole of thy plague: she was so already; but this was a confirmation of it, and what might assure her, that she should remain so, and no more be afflicted with that chastisement. Sin pardoned, though sought for, shall not be found; nor condemnation come upon the pardoned sinner; he is whole and sound, and shall be no more sick, and much less die the second death.

And he said unto her, Daughter--"be of good comfort" (Luke 8:48).
thy faith hath made thee whole; go in peace, and be whole of thy plague--Though healed as soon as she believed, it seemed to her a stolen cure--she feared to acknowledge it. Jesus therefore sets His royal seal upon it. But what a glorious dismissal from the lips of Him who is "our Peace" is that, "Go in peace!"
Jairus' Daughter Raised to Life (Mark 5:35-43).