So that my soul - So that I; the soul being put for himself.
Chooseth strangling - Dr. Good renders it "suffocation," and supposes that Job alludes to the oppression of breathing, produced by what is commonly called the night-mare, and that he means that he would prefer the sense of suffocation excited at such a time to the terrible images before his mind. Herder renders it, death. Jerome, suspendium. The Septuagint, "Thou separatest (ἀπαλλάξεις apallaceis) my life from my spirit, and my bones from death;" but what idea they attached to it, it is impossible now to tell. The Syriac renders it, "Thou choosest my soul from perdition, and my bones from death." The word rendered strangling (מחנק machănaq) is from חנק chânaq, to be narrow, strait, close; and then means to strangle, to throttle, Nahum 2:12; 2-Samuel 17:23. Here it means death; and Job designs to say that he would prefer even the most violent kind of death to the life that he was then leading. I see no evidence that the idea suggested by Dr. Good is to be found in the passage.
And death rather than my life - Margin, as in Hebrew, bones. There has been great variety in the exposition of this part of the verse. Herder renders it, "death rather than this frail body." Rosenmuller and Noyes, "death rather than my bones;" that is, he preferred death to such an emaciated body as he then had, to the wasted skeleton which was then all that he had left to him. This is probably the true sense. Job was a sufferer in body and in soul. His flesh was wasting away, his body was covered with ulcers, and his mind was harassed with apprehensions. By day he had no peace, and at night he was terrified by alarming visions and spectres; and he preferred death in any form to such a condition.

Chooseth strangling - It is very likely that he felt, in those interrupted and dismal slumbers, an oppression and difficulty of breathing something like the incubus or nightmare; and, distressing as this was, he would prefer death by this means to any longer life in such miseries.

So that my soul (k) chooseth strangling, [and] death rather than my life.
(k) He speaks as one overcome with sorrow, and not of judgment, or of the examination of his faith.

So that my soul chooseth strangling,.... Not to strangle himself, as Ahithophel did, or to be strangled by others, this being a kind of death inflicted on capital offenders; but rather, as Mr. Broughton renders it, "to be choked to death" by any distemper and disease, as some are of a suffocating nature, as a catarrh, quinsy, &c. and kill in that way; and indeed death in whatsoever way is the stopping of a man's breath; and it was death that Job chose, let it be in what way it would, whether natural or violent; so weary was he of life through his sore and heavy afflictions:
and death rather than my life; or, "than my bones" (i); which are the more solid parts of the body, and the support of it, and are put for the whole and the life thereof; or than these bones of his, which were full of strong pain, and which had nothing but skin upon them, and that was broken and covered with worms, rottenness, and dust; the Vulgate Latin version renders it, "and my bones death"; that is, desired and chose death, being so full of pain, see Psalm 35:10.
(i) "prae ossibus meis", Montanus, Tigurine version, Bolducius, Cocceius, Schmidt, Schultens; so Mercerus, Piscator, Michaelis.

UMBREIT translates, "So that I could wish to strangle myself--dead by my own hands." He softens this idea of Job's harboring the thought of suicide, by representing it as entertained only in agonizing dreams, and immediately repudiated with horror in Job 7:16, "Yet that (self-strangling) I loathe." This is forcible and graphic. Perhaps the meaning is simply, "My soul chooses (even) strangling (or any violent death) rather than my life," literally, "my bones" (Psalm 35:10); that is, rather than the wasted and diseased skeleton, left to him. In this view, "I loathe it" (Job 7:16) refers to his life.