But you have set yourselves up against me, and reprove me with my reproaches.

If indeed ye will magnify yourselves against me, and prove against me my reproach,

If, truly, over me ye magnify yourselves, And decide against me my reproach;

If you make yourselves great against me, using my punishment as an argument against me,

But you have risen up against me, and you accuse me to my disgrace.

If, indeed, ye will magnify yourselves against me - This is connected with the next verse. The sense is, "all these calamities came from God. He has brought them upon me in a sudden and mysterious manner. In these circumstances you ought to have pity upon me; Job 19:21. Instead of magnifying yourselves against me, setting yourselves up as censors and judges, overwhelming me with reproaches and filling my mind with pain and anguish, you ought to show to me the sympathy of a friend." The phrase, "magnify yourselves," refers to the fact that they had assumed a tone of superiority and an authoritative manner, instead of showing the compassion due to a friend in affliction.
And plead against me my reproach - My calamities as a cause of reproach. You urge them as a proof of the displeasure of God, and you join in reproaching me as a hypocrite. Instead of this, you should have shown compassion to me as a man whom God had greatly afflicted.

If indeed ye will magnify yourselves against me,.... Look and talk big, set up themselves for great folk, and resolve to run him down; open their mouths wide against him and speak great swelling words in a blustering manner; or magnify what they called an error in him, and set it out in the worst light they could:
and plead against me my reproach; his affliction which he was reproached with, and was pleaded against him as an argument of his being a wicked man; if therefore they were determined to go on after this manner, and insist on this kind of proof, then he would have them take what follows.

magnify, &c.--Speak proudly (Obadiah 1:12; Ezekiel 35:13).
against me--emphatically repeated (Psalm 38:16).
plead . . . reproach--English Version makes this part of the protasis, "if" being understood, and the apodosis beginning at Job 19:6. Better with UMBREIT, If ye would become great heroes against me in truth, ye must prove (evince) against me my guilt, or shame, which you assert. In the English Version "reproach" will mean Job's calamities, which they "pleaded" against him as a "reproach," or proof of guilt.