Why do ye persecute me as God? - As God has done. That is, without giving me any reason for it; accusing me of crimes without proof, and condeming me without mitigation. That there is here an improper reflection on God, will be apparent to all. It accords with what Job frequently expresses where he speaks of him as judging him severly, and is on of the instances which prove that he was not entirely perfect.
And are not satisfied with my flesh - That is, are not contented that my "body" is subjected to inexpressible torment, and is wholly wasting away, but add to this the torment of the soul. Why is it not enough that my "body" is thus tormented without adding the severer tortures of the mind?

Why do ye persecute me as God - Are not the afflictions which God sends enough? Do ye not see that I have as much as I can bear? When the papists were burning Dr. Taylor at Oxford, while wrapped in the flames, one of the true sons of the Church took a stick out of the faggots, and threw it at his head, and split open his face. To whom he calmly said, Man, why this wrong? Do not I suffer enough?
And are not satisfied with my flesh? - Will ye persecute my soul, while God is persecuting my body? Is it not enough that my body is destroyed? Why then labor to torment my mind?

Why do ye persecute me as (n) God, and are not satisfied with my (o) flesh?
(n) Is it not enough that God punishes me, unless you by reproaching increase my sorrow?
(o) To see my body punished, unless you trouble my mind?

Why do ye persecute me as God,.... As if they were in his stead, or had the same power and authority over him, who is a sovereign Being, and does what he pleases with his creatures, and is not accountable to any for what he does; but this is not the case of men, nor are they to imitate God in all things; what he does is not in all things a warrant to do the like, or to be pleaded and followed as a precedent by them; they should be merciful as he is merciful, but they are not to afflict and distress his people because he does, and which he does for wise ends and reasons; for such a conduct is resented by him, see Zac 1:15. God persecuted or pursued and followed Job with one affliction after another, and hunted him as a fierce lion does his prey, Job 10:16; but this was not a reason why they should do the same. Some read the words, "why do ye persecute me as those?" (p) you that profess to be my friends, why do ye persecute me as those before mentioned, as those wicked men? or "with those", with such reproaches and calumnies; but the original will not bear it:
and are not satisfied with my flesh? It was not enough that he was afflicted in his body, and his flesh was ulcerated from head to feet, and was clothed with worms and clods of dust; they were not content that his children, which were his own flesh, were tore away from him, and destroyed; and that his substance, which is sometimes called the flesh of men, see Micah 3:3; was devoured, and he was spoiled and plundered of it; but they sought to afflict his mind, to wound his spirit, by their heavy charges and accusations, by their calumnies and reproaches, and hard censures of him; he suggests, that they dealt with him more cruelly than savage beasts, who, when they have got their prey, are satisfied with their flesh; but they, who would be thought to be his friends, were not satisfied with his.
(p) Ben Gersom.

as God--has persecuted me. Prefiguring Jesus Christ (Psalm 69:26). That God afflicts is no reason that man is to add to a sufferer's affliction (Zac 1:15).
satisfied with my flesh--It is not enough that God afflicts my flesh literally (Job 19:20), but you must "eat my flesh" metaphorically (Psalm 27:2); that is, utter the worst calumnies, as the phrase often means in Arabic.

As God - As if you had the same infinite knowledge which God hath, whereby you can search my heart and know my hypocrisy, and the same sovereign authority to say and do what you please with me. Not satisfied - Are like wolves or lions that are not contented with devouring the flesh of their prey, but also break their bones.