Some translate thus, "their inclinations allow them not to turn themselves;" and this meaning is probable, that is, that they were so much given to their own superstitions, that they were not now free, or at liberty, to return to the right way; as though the Prophet said, "They are entirely enslaved by their own diabolical inventions, that their inclinations will not allow them to repent." But the former meaning (it is also more generally approved) seems more adapted to the context. They will not apply, he says, their endeavors to turn to their God Here God declares that it was all over with the people, and that no hope whatever remained: as he said before, "Leave them, why shouldest thou do anything more? for they will not receive wholesome instruction; as they are entirely given up to destruction, there is now no reason for thee to be solicitous about their salvation, for that would be useless;" -- so also he says in this place, They will not apply their endeavors to turn to their God If the Prophet speaks here in his own person, the meaning is, "Why do I weary myself? God has indeed commanded me to reprove this people; but I find that my labour is in vain; for I have to do with brute animals, or with stones rather than with men; there is in them no reason, no discernment; for the devil has fascinated their minds: never, then, will they apply their endeavors to turn to their God." If we prefer to view the sentence as spoken in the person of God, still the doctrine will remain nearly the same: God here declares that the people were incurable. Never, then, will they apply their endeavors. How so? For they are sunk, as it were, into a deep gulf, and their obstinacy is like the abyss. Inasmuch, then, as they are thus fixed in their superstitions, they will never apply their endeavors to turn to their God But God in the meantime not only shows here, that there was no more any remedy for the diseases of the people; but he also gravely and severely reprobates their iniquity, because they thought not of seeking reconciliation with their God; as though he said, "What, then, do I require of these wretched men, but to return to their God? This they ought to have done of their own accord; but now, when they are admonished, they care not; on the contrary, they fiercely resist wholesome instruction. Is not this a strange and monstrous madness?" We hence see that there is an important meaning in the words, They will not apply their endeavors to return to their God; for the Prophet might have simply said, "to return to Jehovah," or "to God;" but he says, to their God, and he says so, because God had made himself familiarly known to them, nay, brought them up in his own bosom, as though they were his children and he their Father: they had forsaken him and had become apostates; and when the Lord would now reprove this perfidy, was it not strange that the people should close their ears and harden their hearts against every instruction? We hence see how sharp this reproof is. And he says, Because the spirit of wantonness is in the midst of them; that is, they are so pleased with their own filthiness, that there is no shame, no fear. But the reason of this comparison, which I have before explained, must be borne in mind. As a wife, though not faithful to her husband, yet retains still some modesty, as long as she continues at home, and while she is in any place classed with faithful and chaste women; but when she once enters a brothel, and openly prostitutes herself to all, when she knows that her baseness is universally known, she then throws off every shame, and entirely forgets her own character: so also the Prophet says, that the spirit of wantonness was in the midst of the people of Israel; as though he said, "The Israelites are so imbrued with their superstitions, that they cannot now be touched or moved by any reverence for God; they cannot be restored to the right way, for the devil has demented them, and having cast off every shame, they are like abominable strumpets." And he afterwards adds, Jehovah they have not known By this sentence the Prophet extenuates not the sin of the people, but, on the contrary, amplifies their ingratitude, because they had forgotten their God, who had so indulgently treated them. As they had been redeemed by God's hand, as the teaching of the law had continued among them, as they had been preserved to that day through God's constant kindness, it was truly an evidence of monstrous ignorance, that they could in an instant adopt ungodly forms of worship, and embrace those corruptions which they knew were condemned in the law. It was surely an inexcusable wickedness in the people thus to withdraw themselves from their God. This is the reason why the Prophet now says, that they knew not Jehovah. But if they were asked the cause, they could not have said that they had no light; for God had made known to them the way of salvation. Hence, that they knew not Jehovah, was to be imputed to their perverseness; for, closing their eyes, they knowingly and willfully ran headlong after those wicked devices, which they knew, as it had been stated before, to be condemned by God.

They will not frame their doings - They were possessed by an evil spirit, impelling and driving them to sin; "the spirit of whoredoms is in the midst of them," i. e., in their very inward self, their center, so to speak; in their souls, where reside the will, the reason, the judgment; and so long as they did not, by the strength of God, dislodge him, they would and could not frame their acts, so as to repent and turn to God. For a mightier impulse mastered them and drove them into sin, as the evil spirit drove the swine into the deep.
The rendering of the margin, although less agreeable to the Hebrew, also gives a striking sense. "Their doings will not suffer them to turn unto their God." Not so much that their habits of sin had got an absolute mastery over them, so as to render repentance impossible; but rather, that it was impossible that they should turn inwardly, while they did not turn outwardly. Their evil doings, so long as they persevered in doing them, took away all heart, whereby to turn to God with a solid conversion.
And yet He was "their God;" this made their sin the more grievous. He, whom they would not turn to, still owned them, was still ready to receive them as "their God." For the prophet continues, "and they have not known the Lord." Him, "their God," they knew not. For the spirit which possessed them hindered them from thought, from memory, from conception of spiritual things. They did not turn to God,
(1) because the evil spirit held them, and so long as they allowed his hold, they were filled with carnal thoughts which kept them back from God.
(2) they did not know God; so that, not knowing how good and how great a good He is in Himself, and how good to us, they had not even the desire to turn to Him, for love of Himself, yea even for love of themselves. They saw not, that they lost a loving God.

They will not frame their doings - They never purpose to turn to God, they have fully imbibed the spirit of idolatry.

They will not frame their doings to turn unto their God,.... Either their evil doings; they will not leave, as the Targum and Jarchi (g); their evil ways and worship, their adultery and idolatry; which was necessary to repentance and true conversion to God, whom they yet professed to be their God, though they had so sadly departed from him: or their good works; they did not choose to do them, which were leading steps to repentance and conversion, or fruits and evidences of it: they had no mind to repent of their sins, and turn from them to the Lord; they had no thought, care, or concern, about these things, but obstinately persisted in their sins and in their impenitence: their wills were wretchedly depraved and corrupted; their hearts hard, perverse, and obstinate; they had no will to that which is good:
for the spirit of whoredom is in the midst of them; an unclean spirit, that prompts them to and pushes them on to commit corporeal and spiritual whoredom; the bias and inclination of their minds were this way which put them upon such evil practices; the spirit of error, which caused them to err, as the Targum and Kimchi; the lying spirit in the false prophets which encouraged them therein; and even himself, the spirit that works in the children of disobedience:
and they have not known the Lord; ignorance of God, his nature and perfections, his will, word, and worship, was the cause of their idolatry, and other sins; see Hosea 4:1; and this was wilful and affected ignorance; they knew not, nor would they understand: they rejected the knowledge of God, and the means of it; so the Targum,
"and they sought not instruction (or doctrine) from the Lord.''
(g) So R. Song. Urbin. fol. 68. 2.

They--Turning from a direct address to Ephraim, he uses the third person plural to characterize the people in general. The Hebrew is against the Margin, their doings will not suffer them" the omission of "them" in the Hebrew after the verb being unusual. The sense is, they are incurable, for they will not permit (as the Hebrew literally means) their doings to be framed so as to turn unto God. Implying that they resist the Spirit of God, not suffering Him to renew them; and give themselves up to "the spirit of whoredoms" (in antithesis to "the Spirit of God" implied in "suffer" or "permit") (Hosea 4:12; Isaiah 63:10; Ezekiel 16:43; Acts 7:51).