Whither shall I go from thy Spirit? I consider that David prosecutes the same idea of its being' impossible that men by any subterfuge should elude the eye of God. By the Spirit of God we are not here, as in several other parts of Scripture, to conceive of his power merely, but his understanding and knowledge. [1] In man the spirit is the seat of intelligence, and so it is here in reference to God, as is plain from the second part of the sentence, where by the face of God is meant his knowledge or inspection. David means in short that he could not change from one place to another without God seeing him, and following him with his eyes as he moved. They misapply the passage who adduce it as a proof of the immensity of God's essence; for though it be an undoubted truth that the glory of the Lord fills heaven and earth, this was not at present in the view of the Psalmist, but the truth that God's eye penetrates heaven and hell, so that, hide in what obscure corner of the world he might, he must be discovered by him. Accordingly he tells us that though he should fly to heaven, or lurk in the lowest abysses, from above or from below all was naked and manifest before God. The wings of the morning, [2] or of Lucifer, is a beautiful metaphor, for when the sun rises on the earth, it transmits its radiance suddenly to all regions of the world, as with the swiftness of flight. The same figure is employed in Malachi 4:2. And the idea is, that though one should fly with the speed of light, he could find no recess where he would be beyond the reach of divine power. For by hand we are to understand power, and the assertion is to the effect that should man attempt to withdraw from the observation of God, it were easy for him to arrest and draw back the fugitive. [3]

Footnotes

1 - Some commentators suppose the third person of the Trinity to be here referred to.

2 - Or "of the dawn of the morning." schr, shachar, the word employed, "is the light which is seen in the clouds before the rising of the sun, and it is like as if it; had wings to fly with haste; for in a moment the dawn of the morning is spread over the horizon, from the end of the east to that of the west." -- Mendlessohn's Beor.

3 - Dathe understands thy hand of God's gracious presence to defend the Psalmist; and such may be the meaning of the words. But whether we take them in this sense, or according to Calvin, as expressing man's being under the power of God, in whatever part of the world he may be, they illustrate the divine omniscience, which Calvin regards as the chief design of the inspired writer.

Whither shall I go from thy spirit? - Where shall I go where thy spirit is not; that is, where thou art not; where there is no God. The word "spirit" here does not refer particularly to the Holy Spirit, but to God "as" a spirit. "Whither shall I go from the all-pervading Spirit - from God, considered as a spirit?" This is a clear statement that God is a "Spirit" (compare John 4:24); and that, as a spirit, he is Omnipresent.
Or whither shall I flee from thy presence? - Hebrew, From his face; that is, where he will not be, and will not see me. I cannot find a place - a spot in the universe, where there is not a God, and the same God. Fearful thought to those that hate him - that, much as they may wish or desire it, they can never find a place where there is not a holy God! Comforting to those that love him - that they will never be where they may not find a God - their God; that nowhere, at home or abroad, on land or on the ocean, on earth or above the stars, they will ever reach a world where they will not be in the presence of that God - that gracious Father - who can defend, comfort, guide, and sustain them.

Whither shall I go from thy Spirit? - Surely רוח ruach in this sense must be taken personally, it certainly cannot mean either breath or wind; to render it so would make the passage ridiculous.
From thy presence? - מפניך mippaneycha, "from thy faces." Why do we meet with this word so frequently in the plural number, when applied to God? And why have we his Spirit, and his appearances or faces, both here? A Trinitarian would at once say, "The plurality of persons in the Godhead is intended;" and who can prove that he is mistaken?

Whither shall I go from thy (e) spirit? or whither shall I flee from thy presence?
(e) From your power and knowledge?

Whither shall I go from thy spirit?.... Or, "from thy wind?" which some interpret literally, the wind being God's creature; which he brings out of his treasures, and holds in his fists, and disposes of as he pleases; this takes its circuit through all the points of the heavens, and blows everywhere, more or less. Rather God himself is meant, who is a Spirit, John 4:24 not a body, or consisting of corporeal parts, which are only ascribed to him in a figurative sense; and who has something analogous to spirit, being simple and uncompounded, invisible, incorruptible, immaterial, and immortal; but is different from all other spirits, being uncreated, eternal, infinite, and immense; so that there is no going from him, as to be out of his sight; nor to any place out of his reach, nor from his wrath and justice, nor so as to escape his righteous judgment. It may signify his all-conscious mind, his all-comprehending understanding and knowledge, which reaches to all persons, places, and things; compare Isaiah 40:13; with Romans 11:34; though it seems best of all to understand it of the third Person, the blessed Spirit, which proceeds from the Father and the Son; and who is possessed of the same perfections, of omniscience, omnipresence, and immensity, as they are; who is the Creator of the heavens and the earth, and pervades them all; and is the Maker of all men, and is present with them to uphold their souls in life, and there is no going from him; particularly he is in all believers, and dwells with them; nor do they desire to go from him, but deprecate his departure from them;
or whither shall I flee from thy presence? which is everywhere, for God's presence is omnipresence; his powerful presence and providence are with all his creatures, to support and uphold them in being; he is not far from, but near to them; in him they live, move, and have their being: and so there is no fleeing from him or that; and as to his gracious presence, which is with all his people, in all places at the same time; they do not desire to flee from it, but always to have it; and are concerned for it, if at any time it is removed from them, as to their apprehension of it. Or, "from thy face" (e); that is, from Christ, who is the face of Jehovah; the image of the invisible God, the express image of his person, in whom all the perfections of God are displayed; and such a likeness, that he that has seen the one has seen the other; he is the Angel of his face or presence, and who always appears before him, and in whom he is seen. Now there is no fleeing from him, for he is everywhere; where God is, his face is: and a sensible sinner desires to flee to him, and not from him; for there is no other refuge to flee unto for life and salvation but to him; and gracious souls desire to be always with him now, and hope to be for ever with him hereafter; they seek him, the face of God, now, and expect to see it more clearly in the world to come.
(e) "a facie tua", Pagninus, Junius & Tremellius, Piscator.

We cannot see God, but he can see us. The psalmist did not desire to go from the Lord. Whither can I go? In the most distant corners of the world, in heaven, or in hell, I cannot go out of thy reach. No veil can hide us from God; not the thickest darkness. No disguise can save any person or action from being seen in the true light by him. Secret haunts of sin are as open before God as the most open villanies. On the other hand, the believer cannot be removed from the supporting, comforting presence of his Almighty Friend. Should the persecutor take his life, his soul will the sooner ascend to heaven. The grave cannot separate his body from the love of his Saviour, who will raise it a glorious body. No outward circumstances can separate him from his Lord. While in the path of duty, he may be happy in any situation, by the exercise of faith, hope, and prayer.