The Lord shall preserve thee from all evil - This is an advance of the thought. The psalmist had in the previous verses specified some particular evils from which he says God would keep those who put their trust in him. He now makes the remark general, and says that God would not only preserve from these particular evils, but would keep those who trusted in him from all evil: he would be their Protector in all the perils of life.
He shall preserve thy soul - Thy life. See Psalm 41:2; Psalm 97:10.

The Lord shall preserve thee from all evil - Spiritual and corporeal, natural and moral.
He shall preserve thy soul - Take care of thy life, and take care of thy soul.

Thee Lord shall preserve them from all evil,.... The Word of the Lord, as the Targum. Not from the evil of affliction, though from that as a penal evil; or as a real one, it being made to work for good: but from the evil of sin; not from the being or commission of it; but from its dominion and damning power, or from a final and total falling away by it: and from the evil of the world; not from tribulation in it, nor from the reproach or persecution of it; but from the wickedness and lusts that are in it, and from the wicked men of it, their power, rage, and fury: and from the evil one, Satan; not from his temptations, but from sinking under them, and perishing by them; see John 17:12;
he shall preserve thy soul: he preserves the bodies of his people, oftentimes from diseases and disasters, and from death, till the appointed time comes; and then he preserves their dust in the grave, and raises it up at the last day; but more especially their souls, the redemption and salvation of which he undertook, and has effected; and which are preserved by him safe to his coming, kingdom, and glory.