The Lord taketh my part with them that help me - The psalmist had friends. There were those who stood by him. He relied, indeed, on their aid, but not on their aid without God. He felt that even their help was valuable to him only as God was with them. There was direct dependence on God in reference to himself; and there was the same sense of dependence in respect to all who were engaged in his defense. This might be rendered, however, simply "for my help," and is so rendered by DeWette. The Septuagint and Latin Vulgate render it, "The Lord is my helper."
Therefore shall I see my desire upon them that hate me - literally, "I shall see upon those that hate me;" that is, I shall look upon them according to my wish; I shall see them overthrown and subdued. See the notes at Psalm 54:7. Compare Psalm 92:11; Psalm 112:8.

The Lord taketh my part with them that help me - Literally, The Lord is to me among my helpers. Therefore shall I see my desire upon them that hate me. Literally, And I shall look among them that hate me. As God is on my side, I fear not to look the whole of them in the face. I shall see them defeated.

The Lord taketh my part with them that help me,.... With the four hundred men that were with David, and stood by him in his troubles, 1-Samuel 22:2; see Psalm 54:4; and with those who ministered unto Christ as man, Luke 8:3. Or, "the Lord is for me, with" or "among my helpers" (t); he is the principal helper, he is one for all; he is in the room and stead of other helpers; having him, there is no need of any other: the Lord is the only helper of his people, vain is the help of man; he helps them out of all their troubles and difficulties, in the exercise of every grace, and in the discharge of every duty; he helps them to all their mercies temporal and spiritual, to grace here, and glory hereafter. The Targum is,
"the Word of the Lord is to help me;''
therefore shall I see my desire upon them that hate me; see "vengeance" on them, as the Targum; which was desired by David, by the Messiah, and by the saints; not for the sake of that itself, but for the glory of divine justice. David saw this, Psalm 54:7; so will the Messiah, when all his enemies, that will not have him to reign over them, will be slain before him; and so will the people of God, when antichrist is destroyed.
(t) "pro me est cum iis qui auxiliantur mihi", Vatablus; so Cocceius, Gejerus.