Lo, your house is left to you desolate. He threatens the destruction of the temple, and the dissolution of the whole frame of civil government. Though they were disfigured by irreligion, crimes, and every kind of infamy, yet they were so blinded by a foolish confidence in the temple, and its outward service, that they thought that God was bound to them; and this was the shield which they had always at hand: "What? Could God depart from that place which he has chosen to be his only habitation in the world? And since he dwells in the midst of us, we must one day be restored." In short, they looked upon the temple as their invincible fortress, as if they dwelt in the bosom of God. But Christ maintains that it is in vain for them to boast of the presence of God, whom they had driven away by their crimes, and, by calling it their house, (lo, your house is left to you,) he indirectly intimates to them that it is no longer the house of God. The temple had indeed been built on the condition, that at the coming of Christ it would cease to be the abode and residence of Deity; but it would have remained as a remarkable demonstration of the continued grace of God, if its destruction had not been occasioned by the wickedness of the people. It was therefore a dreadful vengeance of God, that the place which Himself had so magnificently adorned was not only forsaken by Him, and ordered to be razed to the foundation, but consigned to the lowest infamy to the end of the world. Let the Romanists now go, and let them proceed, in opposition to the will of God, to build their Tower of Babylon, while they see that the temple of God, which had been built by his authority and at his command, was laid low on account of the crimes of the people.

Your house - The temple. The house of worship of the Jews. The chief ornament of Jerusalem.
Desolate - About to be desolate or destroyed. To be forsaken as a place of worship, and delivered into the hands of the Romans, and destroyed. See the notes at Matt. 24.

Behold, your house - Ο οικος, the temple: - this is certainly what is meant. It was once the Lord's temple, God's Own house; but now he says, Your temple or house - to intimate that God had abandoned it. See the note on Matthew 23:21; see also on Luke 13:35 (note).

Behold your house is left unto you desolate. Signifying that the city in which they dwelt, where they had their ceiled houses, and stately palaces, would, in a little time, within the space of forty years, be destroyed, and become a desert; and the temple, formerly the house of God, but now only their's, and in which they trusted, would be abandoned by God, he would grant his presence no more in it; and the Messiah, the proprietor of it, and who was now in it, would then take his leave of it, and never more return to it; and that also should share the same fate as the city, and at the same time. Our Lord seems to have in view those passages in Jeremiah 12:7 and which the Jewish (o) writers understood of the temple. The author of the apocryphal the second book of Esdras has much such an expression as this:
"Thus saith the Almighty Lord, Your house is desolate, I will cast you out as the wind doth stubble.'' (2 Esdras 1:33).
(o) Targum & Kimchi in Jeremiah. xii. 7.

Behold, your house--the temple, beyond all doubt; but their house now, not the Lord's. See on Matthew 22:7.
is left unto you desolate--deserted, that is, of its Divine Inhabitant. But who is that? Hear the next words:

Behold, your house is left unto you desolate. This was the consequence of refusing to come to Christ. The temple is the house meant. God will abandon it and leave it desolate. He will no longer accept its worship.

Behold your house - The temple, which is now your house, not God's: Is left unto you - Our Lord spake this as he was going out of it for the last time: Desolate - Forsaken of God and his Christ, and sentenced to utter destruction.