Verily, I say to you He reproaches them with the blame of preventing him from exerting his power among them as he did in other places, by working miracles: for the unbelief of men presents an obstruction to God, and hinders him from working, as might be desired, for their salvation, (Matthew 13:58; Mark 6:5.) Christ could not perform any miracle among them, because "they did not believe on him," (John 12:37.) Not that it is in the power of men to bind the hands of God, but that he withholds the advantage of his works from those who are rendered unworthy of them by their infidelity. The answer given by Christ amounts to this: "If you wish to have a share in miracles, why do you not give place to God? or rather, why do you proudly reject the minister of his power? You receive, therefore, a just reward for your contempt, when I pass by you, and give a preference to other places, for proving by miracles, that I am the Messiah of God, who have been appointed to restore the church." And, certainly, it was intolerable ingratitude that, when God was pleased to have his Son brought up in their city, such a person, who had been among them from his infancy, was despised. Justly, therefore, did he withdraw his hand, that it might not be exposed to the derision of those wicked despisers. [1] Hence we learn what value the Lord puts on his word, when, in order to punish for the contempt of it, he takes from the midst of us those favors, which are the testimonies of his presence. With respect to that saying, no prophet is acceptable in his own country, the reader may consult what I have said on a saying of the same import, recorded by the Evangelist John: "A prophet hath no honor in his own country," (John 4:44.)

Footnotes

1 - "Afin de n.e servir de passe temps a de si meschans contempteurs des graces de Dieu." -- "That it might not serve for amusement to such wicked despisers of God's favors."

No prophet is accepted - Has honor, or is acknowledged as a prophet. See the notes at Matthew 13:57.

No prophet is accepted - See on Matthew 13:55-57 (note).

And he said, verily I say unto you,.... Another proverb in use among them, the meaning of which was well known to them, and was very appropriate to the present case:
no prophet is accepted in his own country; See Gill on Matthew 13:57

And he said, &c.--He replies to the one proverb by another, equally familiar, which we express in a rougher form--"Too much familiarity breeds contempt." Our Lord's long residence in Nazareth merely as a townsman had made Him too common, incapacitating them for appreciating Him as others did who were less familiar with His everyday demeanor in private life. A most important principle, to which the wise will pay due regard. (See also Matthew 7:6, on which our Lord Himself ever acted.)

No prophet is acceptable in his own country - That is, in his own neighbourhood. It generally holds, that a teacher sent from God is not so acceptable to his neighbours as he is to strangers. The meanness of his family, or lowness of his circumstances, bring his office into contempt: nor can they suffer that he, who was before equal with, or below themselves, should now bear a superior character.