For I am come down from heaven, not that I should do my will, but the will of him that has sent me.

For I have left Heaven and have come down to earth not to seek my own pleasure, but to do the will of Him who sent me.

For I have come down from heaven, not to do my pleasure, but the pleasure of him who sent me.

For I descended from heaven, not to do my own will, but the will of him who sent me.

For I came down from heaven. This is a confirmation of the preceding statement, that we do not seek Christ in vain. For faith is a work of God, by which he shows that we are his people, and appoints his Son to be the protector of our salvation. Now the Son has no other design than to fulfill the commands of his Father. Consequently, he will never reject those whom his Father hath sent. Hence, finally, it follows, that faith will never be useless. As to the distinction which Christ makes between his own will and the will of the Father, in this respect, he accommodates himself to his hearers, because, as the mind of man is prone to distrust, we are wont to contrive some diversity which produces hesitation. To cut off every pretense for those wicked imaginations, Christ declares, that he has been manifested to the world, in order that he may actually ratify what the Father hath decreed concerning our salvation.

For I came down - This verse shows that he came for a specific purpose, which he states in the next verse, and means that, as he came to do his Father's will, he would be faithful to the trust. Though his hearers should reject him, yet the will of God would be accomplished in the salvation of some who should come to Him.
Mine own will - See notes at John 5:30.

Not to do mine own will - I am come, not to act according to human motives, passions, or prejudices; but according to infinite wisdom, goodness, and mercy. Jewish passions and prejudices would reject publicans and sinners as those alluded to, and shut the gate of heaven against the Gentiles; but God's mercy receives them, and I am come to manifest that mercy to men.

For I came down from heaven, not to do mine (k) own will, but the will of him that sent me.
(k) See above in (John 5:22).

For I came down from heaven,.... by change of place, or local motion; for Christ is the immense, infinite, and omnipresent God, and cannot be said properly to move from place to place; for he fills all places, even heaven and earth, with his presence, and was in heaven as the Son of God, at the same time he was here on earth as the son of man: wherefore this must be understood in a manner becoming his proper deity, his divine sonship, and personality: this descent was by the assumption of the human nature into union with his divine person, which was an instance of amazing grace and condescension. The Jew (m) objects to this, and says,
"if this respects the descent of the soul, the soul of every man descended from thence; but if it respects the body, the rest of the evangelists contradict his words, particularly Luke, when he says, Luke 2:7 that his mother brought him forth at Bethlehem.''
But this descent regards neither his soul nor body, but his divine person, which always was in heaven, and not any local descent of that; but, as before observed, an assumption of human nature, which he took of the virgin on earth; and so there is no contradiction between the evangelists; nor is descent from heaven unsuitable to Christ as a divine person, since it is ascribed to God, Genesis 11:7; and if God may be said to go down from heaven by some display of his power, and intimation of his presence, Christ may be said to descend from heaven by that marvellous work of his, taking upon him our nature, and walking up and down on earth in the form of a servant; and which was done with this view, as he says,
not to do mine own will, but the will of him that sent me; that is, not to do his own will, as separate from his Father's, and much less as contrary to it; otherwise he did come to do his own will, which, as God, was the same with his Father's, he being one with him in nature, and so in power and will; and though his will, as man, was distinct from his Father's, yet not repugnant, but resigned unto it: and this will he came to do, was to preach the Gospel, fulfil the law, work miracles, and obtain the eternal redemption and salvation of his people. What the above Jewish writer (n) objects to this part of the text is of very little moment: whose words are;
"moreover, what he says, "not to do mine own will, but the will of him that sent me", shows, that he that sent, is not one and the same with him that is sent, seeing the will of him that is sent, is not as the will of him that sends.''
It is readily granted that they are not one and the same person; they are two distinct persons, which sending, and being sent, do clearly show; but then they are one in nature, though distinct in person, and they agree in will and work. Christ came not to do any will of his own different from that of his Father's; nor do these words imply a difference of wills in them, much less a contrariety in them, but rather the sameness of them.
(m) R. Isaac Chizzuk Emuna, par. 2. c. 44. p. 434. (n) R. Chizzuk Emmuna, par. 2. c. 44. p. 434.

For I came down from heaven not to do Mine own will--to play an independent part.
but--in respect to both the foregoing things, the divine and the human side of salvation.
the will of Him that sent Me--What this twofold will of Him that sent Him is, we are next sublimely told (John 6:39-40):

For I came down from heaven, not to do mine own will. Christ will refuse none who come to him; all such are given by the Father and he came to do the Father's will.