Here the Prophet exhorts the Israelites to flee from Chaldea and Assyria. Yet this exhortation was intended for another purpose, to encourage them in the hope of deliverance; for it was hardly credible that they should ever have a free exit, for Babylon was to them like a sepulcher. As then he exhorts them as to their deliverance, he intimates that God would be their redeemer, as he had promised. But he shows that God's vengeance on Babylon would be dreadful, when he says, Flee from the indignation of God's wrath. We must, however, observe, that the faithful were thus awakened, lest, being inebriated with the indulgences of the Chaldeans, they should obstinately remain there, when God stretched forth his hand to them; for we know what happened when liberty to return was given to the Israelites -- a small portion only returned; some despised the great favor of God; they were so accustomed to their habitations, and were so fixed there, that they made no account of the Temple, nor of the land promised them by God. The Prophet, then, that he might withdraw the faithful from such indulgences, says, that all who, in their torpor, remained there, would be miserable, because the indignation of God would kindle against that city. We now perceive the object of the Prophet. It appears, indeed, but a simple exhortation to the Jews to remove, that they might not be polluted with the filth of Babylon, but another end is also to be regarded, proposed by the holy Prophet. This exhortation, then, contains in it a promise of return, as though he had said, that they were not to fear, because liberty would at length be given them, as God had promised. In the meantime, a stimulant is added to the promise, lest the Israelites should be delighted with the pleasures of Chaldea, and thus despise the inheritance promised them by God; for we know how great was the pleasantness of that land, and how great was the abundance it possessed of all blessings; for the fruitfulness of that land is more celebrated than that of all other countries. No wonder, then, that the Prophet so strongly urged the Jews to return, and that he set before them the vengeance of God to frighten them with terror, in case they slumbered in Chaldea. And he afterwards adds, --

The fierce anger of the Lord - i. e., against Babylon. The people of God are to flee away that they may not be involved in the miseries of Babylon. See the Jeremiah 50:8 note.

My people, go ye out - A warning to all the Jews in Babylon to leave the city, and escape for their lives.

My people, go ye out of the midst of her,.... This is a call of the Jews to go out of Babylon, not before the taking of the city by Cyrus; but when he should issue out a proclamation, giving them liberty to return to their own land; which many of them, being well settled in Babylon, would not be ready to accept of, but choose to continue there; wherefore they are urged to depart from thence, because of the danger they would be exposed unto; for though the city was not destroyed by Cyrus upon his taking it, yet it was by Darius Hystaspes some time after. The same call is given to the people of God to come out of mystical Babylon, Revelation 18:4;
and deliver ye every man his soul from the fierce anger of the Lord; shown in the destruction of Babylon; See Gill on Jeremiah 51:6.

(See on Jeremiah 51:6).

Since Babylon will be punished by the Lord with destruction, the people of God are to flee out of it, and to preserve their lives from the fierce anger of Jahveh, which will discharge itself on Babylon. חרון אף, as in Jeremiah 4:8, Jeremiah 4:26, etc.

Go out of her - At all hazards escape for your lives.