Who can, etc. This fourth point has some affinity to the first, and yet it may be distinguished from it; for the Apostle before taught us that mankind are united to God in the person of one man, as all men partake of the same flesh and nature; but now he refers to another thing, and that is, that the priest ought to be kind and gentle to sinners, because he partakes of their infirmities. The word which the Apostle uses, metriopathein is differently explained both by Greek and Latin interpreters. [1] I, however, think that it simply means one capable of sympathy. All the things which are here said of the Levitical priests do not indeed apply to Christ; for Christ we know was exempt from every contagion of sin; he therefore differed from others in this respect, that he had no necessity of offering a sacrifice for himself. But it is enough for us to know that he bare our infirmities, though free from sin and undefiled. Then, as to the ancient and Levitical priests, the Apostle says, that they were subject to human infirmity, and that they made atonement also for their own sins, that they might not only be kind to others when gone astray, but also condole or sympathize with them. This part ought to be so far applied to Christ as to include that exception which he mentioned before, that is, that he bare our infirmities, being yet without sin. At the same time, though ever free from sin, yet that experience of infirmities before described is alone abundantly sufficient to incline him to help us, to make him merciful and ready to pardon, to render him solicitous for us in our miseries. The sum of what is said is, that Christ is a brother to us, not only on account of unity as to flesh and nature, but also by becoming a partaker of our infirmities, so that he is led, and as it were formed, to show forbearance and kindness. The participle, dunamenos is more forcible than in our common tongue, qui possit, "who can," for it expresses aptness or fitness. The ignorant and those out of the way, or erring, he has named instead of sinners, according to what is done in Hebrew; for sggh, shegage, means every kind of error or offense, as I shall have presently an occasion to explain.

Footnotes

1 - "The classic or philosophic use of the word metriopathein, may be briefly explained. The Stoics maintained that a man should be apathes, i.e., not subject to passions, such as anger, fear, hope, joy, etc. The Platonists on the other hand averred that a wise man should metriopathes, moderate in his affections, and not apathes. The leading sense, then, or the word metriopathein, is to be moderate in our feelings or passions." -- Stuart. But this is not exactly its meaning here. Schleusner, quoting the Greek Lexicographers, shows that it was used in the sense of being indulgent, or of acting kindly and forgivingly, or forebearingly; and this seems to be its meaning in this passage. The sentence is rendered by Macknight, "Being able to have a right measure of compassion on the ignorant and erring." It may be rendered, "Being capable of duly feeling for the ignorant and the erring," or the deceived, that is by sin. See as to the ignorant Leviticus 5:17-19; and as to the deceived by passions or interest, see Leviticus 6:1-7 -- Ed.

Who can have compassion - Margin, "Reasonably bear with." The idea is that of "sympathizing with." The high priest is taken from among men, in order that he may have a fellow-feeling for those on whose behalf he officiates. Sensible of his own ignorance, he is able to sympathize with those who are ignorant; and compassed about with infirmity, he is able to succour those who have like infirmities.
And on them that are out of the way - The erring, and the guilty. If he were taken from an order of beings superior to people, be would be less qualified to sympathize with those who felt that they were sinners, and who needed pardon.
For that he himself also is compassed with infirmity - see chap. Hebrews 7:28. He is liable to err; He is subject to temptation; he must die, and appear before God - and encompassed with these infirmities, he is better qualified to minister in behalf of guilty and dying people. For the same reason it is, that the ministers of the gospel are chosen from among people. They are of like passions with others. They are sinners; they are dying men. They can enter into the feelings of those who are conscious of guilt; they can sympathize with those who tremble in dread of death; they can partake of the emotions of those who expect soon to appear before God.

Who can have compassion on the ignorant - The word μετριοπαθειν, signifies, not merely to have compassion, but to act with moderation, and to bear with each in proportion to his ignorance, weakness, and untoward circumstances, all taken into consideration with the offenses he has committed: in a word, to pity, feel for, and excuse, as far as possible; and, when the provocation is at the highest, to moderate one's passion towards the culprit, and be ready to pardon; and when punishment must be administered, to do it in the gentlest manner.
Instead of αγνοουσι, the ignorant, one MS. only, but that of high repute, has ασθενουσι, the weak. Most men sin much through ignorance, but this does not excuse them if they have within reach the means of instruction. And the great majority of the human race sin through weakness. The principle of evil is strong in them; the occasions of sin are many; through their fall from God they are become exceedingly weak; and what the apostle calls, Hebrews 12:1, that ευπεριστατον ἁμαρτιαν, the well-circumstanced sin, often occurs to every man. But, as in the above ease, weakness itself is no excuse, when the means of strength and succor are always at hand. However, all these are circumstances which the Jewish high priest took into consideration, and they are certainly not less attended to by the High Priest of our profession.
The reason given why the high priest should be slow to punish and prone to forgive is, that he himself is also compassed with weakness; περικειται ασθενειαν; weakness lies all around him, it is his clothing; and as he feels his clothing, so should he feel it; and as he feels it, so he should deplore it, and compassionate others.

Who (c) can have compassion on the ignorant, and (d) on them that are out of the way; for that he himself also is (e) compassed with infirmity.
(c) Fit and meet.
(d) On them that are sinful: for in the Hebrew tongue, under ignorance and error is every sin meant, even that sin that is voluntary.
(e) He carries with him a nature subject to the same inconveniences and vices.

Who can have compassion on the ignorant,.... Who have committed sins of ignorance, and bring their sacrifices for them; these he does not insult and upbraid, nor break out into anger and indignation against; but pities them, and sympathizes with them; has a just measure of compassion suitable to their condition, and bears with them with great moderation and temper:
and on them that are out of the way; of God's commandments; who are like sheep going astray, and turn to their own way; who transgress the law of God, and err from it; perhaps such who sin knowingly and wilfully, and through infirmity, are meant:
for that he himself also is compassed with infirmity; not of body only, but of mind, sinful infirmity; he had much of it, it beset him all around; he was "clothed" with it, as the Syriac version renders it; as Joshua the high priest was with filthy garments, Zac 3:3.

Who can--Greek, "being able"; not pleasing himself (Romans 15:3).
have compassion--Greek, "estimate mildly," "feel leniently," or "moderately towards"; "to make allowance for"; not showing stern rigor save to the obstinate (Hebrews 10:28).
ignorant--sins not committed in resistance of light and knowledge, but as Paul's past sin (1-Timothy 1:13). No sacrifice was appointed for wilful sin committed with a high hand; for such were to be punished with death; all other sins, namely, ignorances and errors, were confessed and expiated with sacrifices by the high priest.
out of the way--not deliberately and altogether wilfully erring, but deluded through the fraud of Satan and their own carnal frailty and thoughtlessness.
infirmity--moral weakness which is sinful, and makes men capable of sin, and so requires to be expiated by sacrifices. This kind of "infirmity" Christ had not; He had the "infirmity" of body whereby He was capable of suffering and death.

Who can have compassion - In proportion to the offence: so the Greek word signifies. On the ignorant - Them that are in error. And the wandering - Them that are in sin. Seeing himself also is compassed with infirmity - Even with sinful infirmity; and so needs the compassion which he shows to others.