Peres - In Daniel 5:25 this is "Upharsin." These are but different forms of the same word - the word in Daniel 5:25 being in the plural, and here in the singular. The verb (פרס peras) means, to "divide;" and in this form, as in the previous cases, it is, according to Gesenius, participle meaning "divided." As it stands here, it would be applicable to anything that was "divided" or "sundered" - whether a kingdom, a palace, a house, territory, etc. "What" was divided could be known only by Divine revelation. If the "word" had been understood by Belshazzar, undoubtedly it would have suggested the idea that there was to be some sort of division or sundering, but what that was to be would not be indicated by the mere use of the word. Perhaps to an affrighted imagination there might have been conveyed the idea that there would be a revolt in some of the provinces of the empire, and that a part would be rent away, but it would not have occurred that it would be so rent that the whole would pass under the dominion of a foreign power. Josephus ("Ant." b. x. ch. xi. Section 3) says, that the word "Phares in the Greek tongue means a "fragment," κλασμα klasma - God will, therefore, break thy kingdom in pieces, and divide it among the Medes and Persians."
Thy kingdom is divided - That is, the proper interpretation of this communication is, that the kingdom is about to be rent asunder, or broken into fragments. It is to be separated or torn from the dynasty that has ruled over it, and to be given to another.
And given to the Medes and Persians - On this united kingdom, see the notes at Isaiah 13:17. It was "given" to the Medes and Persians when it was taken by Cyrus, and when the kingdom of Babylon became extinct, and thenceforward became a part of the Medo-Persian empire. See the notes at Isaiah 13:17, Isaiah 13:19.

PERES,.... The singular of "Pharsin", Daniel 5:25. The sense of this word is,
thy kingdom is divided: which, though it consisted of various provinces, united under Belshazzar, now should be broken and separated from him:
and given to the Medes and Persians; to Darius the Mede, and to Cyrus the Persian, who was a partner for a while with his uncle Darius in the government of the empire: there is an elegant play on words in the words "Peres" and "Persians"; and a grievous thing it is to sinners, not only to have body and soul divided at death, but to be divided and separated from God to all eternity; and to hear that sentence, "depart from me, ye cursed, into everlasting fire, prepared for the devil and his angels".

Peres--the explanation of "dividers" (Daniel 5:25), the active participle plural there being used for the passive participle singular, "dividers" for "divided." The word "Peres" alludes to the similar word "Persia."
divided--namely, among the Medes and Persians [MAURER]; or, "severed" from thee [GROTIUS].

PERES - Separated, divided, broken. Phars signifies two things, broken off, and Persian; noting that, first, this kingdom was broken down from Belshazzar. Secondly, that it was given to the Persians.