They sent them out to Berea. Hereby it appeareth that Paul's labor brought forth fruit in a small time; for though the brethren send forth him and Silas, yet they adjoin themselves as voluntary companions to their danger and cross by this duty. But the constancy of Paul is incredible, because, having had such experience of their stubbornness and malice of his nation, he doth never cease to try whether he can bring any to Christ, namely, seeing he knew that he was bound both to Jews and Gentiles, no injury of men could lead him away from his calling. So all the servants of Christ must so wrestle with the malice of the world, that they shake not off Christ's yoke with what injuries soever they be provoked.

And the brethren immediately sent away Paul and Silas - Compare Acts 9:25. They did this for their safety. Yet this was not done until the gospel had taken deep root in Thessalonica. Having preached there, and laid the foundation of a church; having thus accomplished the purpose for which they went there, they prepared to leave the city.
Unto Berea - This was a city of Macedonia, near Mount Cithanes. "Bercea is on the eastern slope of the Olympian range, and commands an extensive view of the plain which is watered by the Haliacmon and Axius. It has many natural advantages, and is now considered one of the most agreeable towns in Rumili. Plane trees spread a grateful shade over its gardens. Streams of water are in every street. Its ancient name is said to have been derived from the abundance of its waters; and the name still survives in the modern Verria, or Kara-Verria. It is situated o the left of the Haliacmon, about 5 miles from the point where that river breaks through an immense rocky ravine from the mountains to the plain. A few insignificant ruins of the Greek and Roman periods may yet be noticed. It still boasts of 18,000 or 20,000 inhabitants, and is placed in the second rank of the cities of European Turkey" - Life and Epistles of Paul.

Sent away Paul and Silas by night - Fearing some farther machinations of the Jews and their associates.
Berea - This was another city of Macedonia, on the same gulf with Thessalonica; and not far from Pella, the birth place of Alexander the Great.

(4) And the brethren immediately sent away Paul and Silas by night unto Berea: who coming [thither] went into the synagogue of the Jews.
(4) That is indeed the wisdom of the Spirit which always sets the glory of God before itself as a mark with which it directs itself, and never wavers from it.

And the brethren,.... The believers in Thessalonica, the young converts there, who were full of love and affection to their spiritual fathers:
immediately sent away Paul and Silas by night unto Berea; another city in Macedonia: and so it is placed by Pliny (l) in the north part of it; and, according to Ptolomy (m) it was, in that part of Macedonia called Emathia, and was not far from Pella, the native place of Alexander the great. It is now called Veria; some say it was called Berea from Beraea, daughter of Beres, son of Macedo, by whom it is said to have been built; others from Pheron; and some think it has some agreement with the Syriac word Barja and Baraitha; since what is called Berytus, is Beroe with others: there was besides this another Beraea, a city of Syria, which Josephus (n) speaks of; and is mentioned by Pliny (o) along with Hierapolis and Chalcis, and very likely is the same that is spoken of in:
"But the King of kings moved Antiochus' mind against this wicked wretch, and Lysias informed the king that this man was the cause of all mischief, so that the king commanded to bring him unto Berea, and to put him to death, as the manner is in that place.'' (2 Maccabees 13:4)
Hither the brethren sent Paul and Silas, when it was night and dark, and they could pass unobserved, in order to preserve them from the fury of the mob.
Who coming thither; to Berea; that is, Paul and Silas:
went into the synagogue of the Jews; which was in that city; not being at all daunted or discouraged with what they had met with at Thessalonica.
(l) Nat. Hist. l. 4. c. 10. (m) Geograph. l. 3. c. 13. (n) Antiqu. l. 12. c. 8. sect. 7. (o) Nat. Hist. l. 5. c. 23, 26.

The Jews in Berea applied seriously to the study of the word preached unto them. They not only heard Paul preach on the sabbath, but daily searched the Scriptures, and compared what they read with the facts related to them. The doctrine of Christ does not fear inquiry; advocates for his cause desire no more than that people will fully and fairly examine whether things are so or not. Those are truly noble, and likely to be more and more so, who make the Scriptures their rule, and consult them accordingly. May all the hearers of the gospel become like those of Berea, receiving the word with readiness of mind, and searching the Scriptures daily, whether the things preached to them are so.

the brethren immediately sent away Paul and Silas by night--for it would have been as useless as rash to attempt any further preaching at that time, and the conviction of this probably made his friends the more willing to pledge themselves against any present continuance of missionary effort.
unto Berea--fifty or sixty miles southwest of Thessalonica; a town even still of considerable population and importance.

Sent away Paul and Silas by night. By night so as to leave without a fresh disturbance.
Unto Berea. Howson places Berea sixty, Hackett forty-five, miles west of Thessalonica. The first states that it now has 18,000 population, and is called Verria.
Many of them believed. This would be the natural result. As elsewhere, the converts were Jews and devout Greeks, both men and women.
Honourable. Of high rank.