The prophets - None of the prophets of this reign are certainly known. One may possibly have been Hosai or Hozai (2-Chronicles 33:19, margin), who perhaps wrote a life of Manasseh.

The Lord spake by - the prophets - The prophets were Hosea, Joel, Nahum, Habakkuk, and Isaiah. These five following verses contain the sum of what these prophets spoke. It is said that Isaiah not only prophesied in those days, but also that he was put to death by Manasseh, being sawn asunder by a wooden saw.

And the Lord spake by his servants the prophets,.... Who prophesied in the days of Manasseh; and were, according to the Jewish chronology (f), Joel, Nahum, and Habakkuk:
saying: as follows.
(f) Seder Olam Rabba, c. 20. p. 55.

Here is the doom of Judah and Jerusalem. The words used represent the city emptied and utterly desolate, yet not destroyed thereby, but cleansed, and to be kept for the future dwelling of the Jews: forsaken, yet not finally, and only as to outward privileges, for individual believers were preserved in that visitation. The Lord will cast off any professing people who dishonour him by their crimes, but never will desert his cause on earth. In the book of Chronicles we read of Manasseh's repentance, and acceptance with God; thus we may learn not to despair of the recovery of the greatest sinners. But let none dare to persist in sin, presuming that they may repent and reform when they please. There are a few instances of the conversion of notorious sinners, that none may despair; and but few, that none may presume.

And the Lord spake by his servants the prophets--These were Hosea, Joel, Nahum, Habakkuk, and Isaiah. Their counsels, admonitions, and prophetic warnings, were put on record in the national chronicles (2-Chronicles 33:18) and now form part of the sacred canon.