18 'Of your sons who shall issue from you, whom you shall father, shall they take away; and they shall be eunuchs in the palace of the king of Babylon.'"
*Minor differences ignored. Grouped by changes, with first version listed as example.
This prophecy had two fulfillments, each complementary to the other. Manasseh, Hezekiah's actual son, was "carried to Babylon" 2-Chronicles 33:11, but did not become a eunuch in the palace. Daniel and others, not his actual sons, but of the royal seed Daniel 1:3, and therefore Hezekiah's descendants, are thought by some to have literally fulfilled the latter part of the prophecy, being eunuchs in the palace of Nebuchadnezzar.
They shall be eunuchs - Perhaps this means no more than that they should become household servants to the kings of Babylon. See the fulfillment, 2-Kings 24:13-15, and Daniel 1:1-3.
The words, "of thy sons, which shall proceed from thee, which thou shalt beget," do not necessarily refer to the actual sons, but only to lineal descendants. The Chethb יקּח, "will one take," is to be preferred to the יקּחוּ of Isaiah and the Keri, as being the more difficult reading. סריסים, chamberlains, courtiers, not necessarily eunuchs, as in 1-Samuel 8:15, etc. - For the fulfilment of this threat see Daniel 1:2.
Thy sons - Of thy grand - children. Eunuchs - They shall be servants to that heathen monarch, whereby both their bodies will be subject to slavery, and their souls exposed to the peril of idolatry, and all sorts of wickedness.
*More commentary available at chapter level.