What prayer and supplication soever be made by any man, or by all thy people Israel, which shall know every man the plague of his own heart, and spread forth his hands toward this house:

Whatsoever curse or imprecation shall happen to any man of thy people Israel: when a man shall know the wound of his own heart, and shall spread forth his hands in this house,

Whatever prayer and supplication shall be made by any man, or by all thy people Israel, who shall know every man the plague of his own heart, and spread forth his hands towards this house:

any prayer, any supplication that is of any man of all Thy people Israel, who know each the plague of his own heart, and hath spread his hands towards this house,

Whatever prayer or request for your grace is made by any man, or by all your people Israel, whatever his trouble may be, whose hands are stretched out to this house:

whatever prayer and petition is made by any man, or by all your people Israel, who shall each know the plague of his own heart, and spread forth his hands toward this house:

or whatever curse or divine intervention may happen to any man among your people Israel, if anyone understands, having been wounded in his heart, and if he will have extended his hands in this house,

Know every man the plague of his own heart - i. e. perceive one's sinfulness, or recognize one's sufferings as divine chastisements, and sin as their cause.

What prayer and supplication soever be [made] by any man, [or] by all thy people Israel, which shall know every man the plague of his own (o) heart, and spread forth his hands toward this house:
(o) For such are most suitable to receive God's mercies.

What prayer and supplication soever,.... On account of any of the above things, or any other:
be made by any man, or by all the people Israel; by a private man, for such an one might go to the temple and pray by himself; see Luke 18:10 or by the public congregation:
which shall know every man the plague of his own heart; be sensible of his sin as the cause of his distress, and own it, though ever so privately committed, which none knows but God and his own heart; and which may be only an heart sin, not actually committed; as all sin is originally in the heart, and springs from it, that is the source of all wickedness; it may respect the corruption of nature, indwelling sin, which truly deserves this name, and which every good man is led to observe, confess, and bewail, Psalm 51:4. In 2-Chronicles 6:29 it is,
shall know his own sore and his own grief; what particularly affects him, and gives him pain and sorrow, as every man best knows his own affliction and trouble, and so can best represent his own case to the Lord:
and spread forth his hands towards this house; pray with his face towards it, and his hands spread out, a prayer gesture, and what was now used by Solomon, 1-Kings 8:22.

The plague - His sin, which may be called the plague of his heart, in opposition to the other plagues here mentioned; so the sense is, who, by their afflictions are brought to a true and serious sense of their worse and inward plague of their sins, which are most fitly called the plague of the heart, because that is both the principal seat of sin, and the fountain from whence all actual sins flow.